Gene description for Sncg
Gene name synuclein, gamma
Gene symbol Sncg
Other names/aliases -
Species Rattus norvegicus
 Database cross references - Sncg
ExoCarta ExoCarta_64347
Entrez Gene 64347
UniProt Q63544  
 Sncg identified in exosomes derived from the following tissue/cell type
Adipocytes 25998041    
 Gene ontology annotations for Sncg
Molecular Function
    protein binding GO:0005515 IPI
    beta-tubulin binding GO:0048487 IDA
    alpha-tubulin binding GO:0043014 IDA
Biological Process
    synapse organization GO:0050808 ISO
    response to cocaine GO:0042220 IEP
    protein secretion GO:0009306 ISO
    regulation of neurotransmitter secretion GO:0046928 ISO
    synaptic transmission GO:0007268 ISO
    response to drug GO:0042493 IEP
    regulation of dopamine secretion GO:0014059 ISO
    cellular response to hydrostatic pressure GO:0071464 IEP
    peripheral nervous system development GO:0007422 NAS
    aggressive behavior GO:0002118 IEP
    adult locomotory behavior GO:0008344 ISO
Subcellular Localization
    extracellular exosome GO:0070062 ISO
    plasma membrane GO:0005886 IDA
    spindle GO:0005819 IEA
    microtubule organizing center GO:0005815 IEA
    axon terminus GO:0043679 IDA
    axon GO:0030424 ISO
    cytoplasm GO:0005737 ISO
    neuronal cell body GO:0043025 ISO
    perinuclear region of cytoplasm GO:0048471 IDA
 Experiment description of studies that identified Sncg in exosomes
1
Experiment ID 225
ISEV standards
✔
EM
EV Biophysical techniques
✔
GAPDH
EV Cytosolic markers
✔
CD63
EV Membrane markers
✘ EV Negative markers
✔
NTA
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25998041    
Organism Rattus norvegicus
Experiment description Proteomic Analysis of Extracellular Vesicles Released by Adipocytes of Otsuka Long-Evans Tokushima Fatty (OLETF) Rats.
Authors Lee JE, Moon PG, Lee IK, Baek MC
Journal name Protein J
Publication year 2015
Sample Adipocytes
Sample name Adipocytes
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
 Protein-protein interactions for Sncg
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Sncg is involved
No pathways found





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