Gene description for Sncg
Gene name synuclein, gamma
Gene symbol Sncg
Other names/aliases -
Species Rattus norvegicus
 Database cross references - Sncg
ExoCarta ExoCarta_64347
Vesiclepedia VP_64347
Entrez Gene 64347
UniProt Q63544  
 Sncg identified in sEVs derived from the following tissue/cell type
Adipocytes 25998041    
 Gene ontology annotations for Sncg
Molecular Function
    protein binding GO:0005515 IPI
    alpha-tubulin binding GO:0043014 IDA
    beta-tubulin binding GO:0048487 IDA
    cuprous ion binding GO:1903136 IBA
Biological Process
    aggressive behavior GO:0002118 IEP
    chemical synaptic transmission GO:0007268 IBA
    chemical synaptic transmission GO:0007268 IEA
    chemical synaptic transmission GO:0007268 ISO
    peripheral nervous system development GO:0007422 NAS
    adult locomotory behavior GO:0008344 IEA
    adult locomotory behavior GO:0008344 ISO
    protein secretion GO:0009306 IEA
    protein secretion GO:0009306 ISO
    response to xenobiotic stimulus GO:0009410 IEP
    regulation of dopamine secretion GO:0014059 IEA
    regulation of dopamine secretion GO:0014059 ISO
    response to cocaine GO:0042220 IEP
    regulation of neurotransmitter secretion GO:0046928 IEA
    regulation of neurotransmitter secretion GO:0046928 ISO
    synaptic vesicle endocytosis GO:0048488 IBA
    synapse organization GO:0050808 IBA
    synapse organization GO:0050808 IEA
    synapse organization GO:0050808 ISO
    cellular response to hydrostatic pressure GO:0071464 IEP
    regulation of cellular response to stress GO:0080135 IMP
    response to desipramine GO:1904307 IEP
Subcellular Localization
    cytoplasm GO:0005737 IBA
    cytoplasm GO:0005737 IEA
    cytoplasm GO:0005737 ISO
    centrosome GO:0005813 IEA
    centrosome GO:0005813 ISO
    spindle GO:0005819 IEA
    axon GO:0030424 IEA
    axon GO:0030424 ISO
    neuronal cell body GO:0043025 IBA
    neuronal cell body GO:0043025 IDA
    neuronal cell body GO:0043025 IEA
    neuronal cell body GO:0043025 ISO
    axon terminus GO:0043679 IBA
    axon terminus GO:0043679 IDA
    synapse GO:0045202 IEA
    perinuclear region of cytoplasm GO:0048471 IDA
 Experiment description of studies that identified Sncg in sEVs
1
Experiment ID 225
MISEV standards
✔
EM
Biophysical techniques
✔
GAPDH|CD63
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25998041    
Organism Rattus norvegicus
Experiment description Proteomic Analysis of Extracellular Vesicles Released by Adipocytes of Otsuka Long-Evans Tokushima Fatty (OLETF) Rats.
Authors "Lee JE, Moon PG, Lee IK, Baek MC"
Journal name Protein J
Publication year 2015
Sample Adipocytes
Sample name Adipocytes
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
 Protein-protein interactions for Sncg
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Sncg is involved
No pathways found





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