Gene description for Aldh1l1
Gene name aldehyde dehydrogenase 1 family, member L1
Gene symbol Aldh1l1
Other names/aliases FDH
Fthfd
Species Rattus norvegicus
 Database cross references - Aldh1l1
ExoCarta ExoCarta_64392
Vesiclepedia VP_64392
Entrez Gene 64392
UniProt P28037  
 Aldh1l1 identified in sEVs derived from the following tissue/cell type
Hepatocytes 19367702    
 Gene ontology annotations for Aldh1l1
Molecular Function
    aldehyde dehydrogenase (NAD+) activity GO:0004029 IBA
    aldehyde dehydrogenase [NAD(P)+] activity GO:0004030 IDA
    formyltetrahydrofolate dehydrogenase activity GO:0016155 IBA
    formyltetrahydrofolate dehydrogenase activity GO:0016155 IDA
    formyltetrahydrofolate dehydrogenase activity GO:0016155 IEA
    formyltetrahydrofolate dehydrogenase activity GO:0016155 IMP
    formyltetrahydrofolate dehydrogenase activity GO:0016155 ISO
    formyltetrahydrofolate dehydrogenase activity GO:0016155 TAS
    oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor GO:0016620 IEA
    aldehyde dehydrogenase (NADP+) activity GO:0033721 IDA
    protein-containing complex binding GO:0044877 IDA
Biological Process
    one-carbon metabolic process GO:0006730 IEA
    NADPH regeneration GO:0006740 IDA
    NADPH regeneration GO:0006740 IEA
    NADPH regeneration GO:0006740 ISO
    biosynthetic process GO:0009058 IEA
    10-formyltetrahydrofolate catabolic process GO:0009258 IDA
    10-formyltetrahydrofolate catabolic process GO:0009258 IEA
    10-formyltetrahydrofolate catabolic process GO:0009258 IMP
    10-formyltetrahydrofolate catabolic process GO:0009258 ISO
    tetrahydrofolate biosynthetic process GO:0046654 TAS
    folic acid metabolic process GO:0046655 IDA
Subcellular Localization
    mitochondrion GO:0005739 ISO
    cytosol GO:0005829 IDA
    cytosol GO:0005829 IEA
    cytosol GO:0005829 ISO
    protein-containing complex GO:0032991 IDA
 Experiment description of studies that identified Aldh1l1 in sEVs
1
Experiment ID 35
MISEV standards
CEM
Biophysical techniques
TSG101|Alix|CD81|CD63
Enriched markers
HSPA5
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19367702    
Organism Rattus norvegicus
Experiment description Characterization and Comprehensive Proteome Profiling of Exosomes Secreted by Hepatocytes.
Authors "Conde-Vancells J, Rodriguez-Suarez E, Embade N, Gil D, Matthiesen R, Valle M, Elortza F, Lu SC, Mato JM, Falcon-Perez JM"
Journal name JPR
Publication year 2008
Sample Hepatocytes
Sample name Hepatocytes
Isolation/purification methods Differential centrifugation
Filtration
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [QTOF]
Western blotting
 Protein-protein interactions for Aldh1l1
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.



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