Gene description for Cdc42
Gene name	cell division cycle 42
Gene symbol	Cdc42
Other names/aliases	-
Species	Rattus norvegicus
Database cross references - Cdc42
ExoCarta	ExoCarta_64465
Entrez Gene	64465
UniProt	Q8CFN2
Cdc42 identified in exosomes derived from the following tissue/cell type
Reticulocytes	21828046
Reticulocytes	21828046
Reticulocytes	21828046
Reticulocytes	21828046
Reticulocytes	21828046
Reticulocytes	21828046
Reticulocytes	21828046
Reticulocytes	21828046
Reticulocytes	21828046
Urine	20535238

Gene ontology annotations for Cdc42

Molecular Function     identical protein binding GO:0042802 ISO     mitogen-activated protein kinase kinase kinase binding GO:0031435 IPI     protein binding GO:0005515 IPI     thioesterase binding GO:0031996 ISO     GTPase activity GO:0003924 TAS     apolipoprotein A-I receptor binding GO:0034191 ISO     GTP-dependent protein binding GO:0030742 ISO     GTP binding GO:0005525 TAS     protein kinase binding GO:0019901 ISO Biological Process     positive regulation of DNA replication GO:0045740 IMP     regulation of filopodium assembly GO:0051489 ISS     positive regulation of intracellular protein transport GO:0090316 IMP     filopodium assembly GO:0046847 ISO     actin filament bundle assembly GO:0051017 ISO     regulation of protein metabolic process GO:0051246 ISO     keratinocyte development GO:0003334 ISO     actin cytoskeleton organization GO:0030036 ISO     response to glucose GO:0009749 TAS     positive regulation of cytokinesis GO:0032467 ISS     small GTPase mediated signal transduction GO:0007264 IEA     hair follicle morphogenesis GO:0031069 ISO     positive regulation of synapse structural plasticity GO:0051835 IMP     endocytosis GO:0006897 ISO     negative regulation of protein complex assembly GO:0031333 ISO     positive regulation of neuron apoptotic process GO:0043525 IMP     negative regulation of gene expression GO:0010629 ISO     establishment of cell polarity GO:0030010 TAS     canonical Wnt signaling pathway GO:0060070 ISO     nucleus localization GO:0051647 ISO     epithelial-mesenchymal cell signaling GO:0060684 ISO     submandibular salivary gland formation GO:0060661 IEP     positive regulation of JNK cascade GO:0046330 IDA     regulation of protein heterodimerization activity GO:0043497 ISO     hair follicle placode formation GO:0060789 ISO     positive regulation of MAPK cascade GO:0043410 ISO     heart contraction GO:0060047 ISO     establishment of Golgi localization GO:0051683 IMP     epidermis morphogenesis GO:0048730 ISO     actin filament branching GO:0090135 IMP     keratinization GO:0031424 ISO     neuron fate determination GO:0048664 ISO     positive regulation of peptidyl-serine phosphorylation GO:0033138 ISO     metabolic process GO:0008152 TAS     sprouting angiogenesis GO:0002040 IMP     positive regulation of pseudopodium assembly GO:0031274 ISO     single organismal cell-cell adhesion GO:0016337 ISO     regulation of protein kinase activity GO:0045859 ISO     regulation of exocytosis GO:0017157 TAS     actin filament organization GO:0007015 IMP     cardiac conduction system development GO:0003161 ISO     epithelial cell-cell adhesion GO:0090136 ISO     substantia nigra development GO:0021762 ISO     positive regulation of protein phosphorylation GO:0001934 ISO     establishment or maintenance of apical/basal cell polarity GO:0035088 ISO     adherens junction organization GO:0034332 ISO     regulation of attachment of spindle microtubules to kinetochore GO:0051988 ISS     regulation of mitotic nuclear division GO:0007088 ISO     multicellular organism growth GO:0035264 ISO     dendritic cell migration GO:0036336 ISO     positive regulation of hair follicle cell proliferation GO:0071338 ISO     positive regulation of metalloenzyme activity GO:0048554 IMP     Golgi organization GO:0007030 IMP     organelle transport along microtubule GO:0072384 IMP     positive regulation of substrate adhesion-dependent cell spreading GO:1900026 ISS     cellular protein localization GO:0034613 ISO     positive regulation of phosphatidylinositol 3-kinase activity GO:0043552 ISO     positive regulation of gene expression GO:0010628 ISO     regulation of protein stability GO:0031647 ISO     nuclear migration GO:0007097 ISO     regulation of protein catabolic process GO:0042176 ISO Subcellular Localization     neuronal cell body GO:0043025 ISO     apical part of cell GO:0045177 ISO     microtubule organizing center GO:0005815 IEA     cell periphery GO:0071944 ISO     cytosol GO:0005829 TAS     cytoplasmic ribonucleoprotein granule GO:0036464 ISO     cell GO:0005623 ISO     extracellular exosome GO:0070062 ISO     storage vacuole GO:0000322 ISO     cell projection GO:0042995 ISO     membrane GO:0016020 ISS     cytoplasm GO:0005737 ISO     neuron projection GO:0043005 ISO     midbody GO:0030496 ISS     cell-cell junction GO:0005911 ISO     spindle midzone GO:0051233 ISS     plasma membrane GO:0005886 ISO     mitotic spindle GO:0072686 ISS     myelin sheath GO:0043209 ISO     leading edge membrane GO:0031256 ISO     focal adhesion GO:0005925 ISO     secretory granule GO:0030141 IDA     filopodium GO:0030175 ISO     Golgi membrane GO:0000139 IDA