Gene description for Entpd2
Gene name ectonucleoside triphosphate diphosphohydrolase 2
Gene symbol Entpd2
Other names/aliases Cd39l1
NTPDase2
Species Rattus norvegicus
 Database cross references - Entpd2
ExoCarta ExoCarta_64467
Entrez Gene 64467
UniProt O35795  
 Entpd2 identified in exosomes derived from the following tissue/cell type
Adipocytes 25998041    
 Gene ontology annotations for Entpd2
Molecular Function
    ATP binding GO:0005524 IEA
    hydrolase activity GO:0016787 IEA
    nucleoside-triphosphatase activity GO:0017111 ISO
    adenosine-diphosphatase activity GO:0043262 IDA
    identical protein binding GO:0042802 IDA
    nucleoside-diphosphatase activity GO:0017110 ISO
    ATPase activity GO:0016887 IDA
    nucleotide binding GO:0000166 IEA
Biological Process
    response to auditory stimulus GO:0010996 IEP
    metabolic process GO:0008152 IEA
    protein homooligomerization GO:0051260 IDA
    cellular response to interleukin-6 GO:0071354 IMP
    G-protein coupled receptor signaling pathway GO:0007186 ISO
    cellular response to interferon-alpha GO:0035457 IEP
    purine ribonucleoside diphosphate catabolic process GO:0009181 ISO
    platelet activation GO:0030168 ISO
    cellular response to lipopolysaccharide GO:0071222 IEP
    cellular response to tumor necrosis factor GO:0071356 IEP
Subcellular Localization
    basal lamina GO:0005605 ISO
    integral component of membrane GO:0016021 IEA
    plasma membrane GO:0005886 ISO
    extracellular exosome GO:0070062 ISO
    cell body GO:0044297 IDA
    cell surface GO:0009986 IDA
    cell projection membrane GO:0031253 IDA
 Experiment description of studies that identified Entpd2 in exosomes
1
Experiment ID 225
ISEV standards
✔
EM
EV Biophysical techniques
✔
GAPDH
EV Cytosolic markers
✔
CD63
EV Membrane markers
✘ EV Negative markers
✔
NTA
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25998041    
Organism Rattus norvegicus
Experiment description Proteomic Analysis of Extracellular Vesicles Released by Adipocytes of Otsuka Long-Evans Tokushima Fatty (OLETF) Rats.
Authors Lee JE, Moon PG, Lee IK, Baek MC
Journal name Protein J
Publication year 2015
Sample Adipocytes
Sample name Adipocytes
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
 Protein-protein interactions for Entpd2
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Entpd2 is involved
No pathways found





Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here