Gene description for Eif2b1
Gene name	eukaryotic translation initiation factor 2B, subunit 1 alpha
Gene symbol	Eif2b1
Other names/aliases	eIF-2a
Species	Rattus norvegicus
Database cross references - Eif2b1
ExoCarta	ExoCarta_64514
Vesiclepedia	VP_64514
Entrez Gene	64514
UniProt	Q64270
Eif2b1 identified in sEVs derived from the following tissue/cell type
Reticulocytes	21828046

Gene ontology annotations for Eif2b1

Molecular Function     translation initiation factor activity GO:0003743 IBA     translation initiation factor activity GO:0003743 IDA     translation initiation factor activity GO:0003743 IEA     translation initiation factor activity GO:0003743 ISO     translation initiation factor activity GO:0003743 ISS     guanyl-nucleotide exchange factor activity GO:0005085 IBA     guanyl-nucleotide exchange factor activity GO:0005085 IDA     guanyl-nucleotide exchange factor activity GO:0005085 IEA     guanyl-nucleotide exchange factor activity GO:0005085 ISO     guanyl-nucleotide exchange factor activity GO:0005085 ISO     guanyl-nucleotide exchange factor activity GO:0005085 ISS     GTP binding GO:0005525 IMP     GDP binding GO:0019003 IDA     identical protein binding GO:0042802 IEA     identical protein binding GO:0042802 ISO Biological Process     cytoplasmic translational initiation GO:0002183 IEA     cytoplasmic translational initiation GO:0002183 ISO     cytoplasmic translational initiation GO:0002183 ISS     translation GO:0006412 IDA     translational initiation GO:0006413 IBA     translational initiation GO:0006413 IDA     translational initiation GO:0006413 IEA     translational initiation GO:0006413 ISO     translational initiation GO:0006413 ISS     response to heat GO:0009408 IDA     response to glucose GO:0009749 IDA     oligodendrocyte development GO:0014003 IEA     oligodendrocyte development GO:0014003 ISO     oligodendrocyte development GO:0014003 ISS     response to peptide hormone GO:0043434 IDA     T cell receptor signaling pathway GO:0050852 IEA     T cell receptor signaling pathway GO:0050852 ISO     T cell receptor signaling pathway GO:0050852 ISS     negative regulation of guanyl-nucleotide exchange factor activity GO:1905098 IDA     response to amino acid starvation GO:1990928 IDA Subcellular Localization     cytoplasm GO:0005737 ISO     cytoplasm GO:0005737 ISS     cytosol GO:0005829 IEA     eukaryotic translation initiation factor 2 complex GO:0005850 IDA     eukaryotic translation initiation factor 2B complex GO:0005851 IBA     eukaryotic translation initiation factor 2B complex GO:0005851 IDA     eukaryotic translation initiation factor 2B complex GO:0005851 IEA     eukaryotic translation initiation factor 2B complex GO:0005851 ISO     eukaryotic translation initiation factor 2B complex GO:0005851 ISS     plasma membrane GO:0005886 IEA     plasma membrane GO:0005886 ISO     membrane GO:0016020 ISO