Gene description for Fgfbp1
Gene name fibroblast growth factor binding protein 1
Gene symbol Fgfbp1
Other names/aliases -
Species Rattus norvegicus
 Database cross references - Fgfbp1
ExoCarta ExoCarta_64535
Entrez Gene 64535
UniProt Q9QY10  
 Fgfbp1 identified in exosomes derived from the following tissue/cell type
Pancreatic cancer cells 20124479    
Pancreatic cancer cells 20124479    
 Gene ontology annotations for Fgfbp1
Molecular Function
    growth factor binding GO:0019838 IEA
    fibroblast growth factor binding GO:0017134 ISO
Biological Process
    positive regulation of defense response to virus by host GO:0002230 ISO
    cell-cell signaling GO:0007267 IDA
    positive regulation of cell proliferation GO:0008284 ISO
    activation of mitophagy in response to mitochondrial depolarization GO:0098779 ISO
    positive regulation of fibroblast growth factor receptor signaling pathway GO:0045743 ISO
Subcellular Localization
    extracellular space GO:0005615 IEA
    plasma membrane GO:0005886 IEA
    cell surface GO:0009986 ISO
    extracellular region GO:0005576 ISO
 Experiment description of studies that identified Fgfbp1 in exosomes
1
Experiment ID 92
ISEV standards
EM
EV Biophysical techniques
HSP70|GAPDH
EV Cytosolic markers
CD9|CD151
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule mrna
Identification method RT-PCR
Microarray
PubMed ID 20124479    
Organism Rattus norvegicus
Experiment description Cell surface tetraspanin Tspan8 contributes to molecular pathways of exosome-induced endothelial cell activation.
Authors Nazarenko I, Rana S, Baumann A, McAlear J, Hellwig A, Trendelenburg M, Lochnit G, Preissner KT, Zoller M.
Journal name CR
Publication year 2010
Sample Pancreatic cancer cells
Sample name AS
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density 1.14-1.17 g/mL
Molecules identified in the study Protein
mRNA
Methods used in the study RT-PCR
Western blotting
RatRef-12 Microarray
FACS
Mass spectrometry [MALDI TOF]
2
Experiment ID 93
ISEV standards
EM
EV Biophysical techniques
HSP70|GAPDH
EV Cytosolic markers
CD9|CD151
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule mrna
Identification method RT-PCR
Microarray
PubMed ID 20124479    
Organism Rattus norvegicus
Experiment description Cell surface tetraspanin Tspan8 contributes to molecular pathways of exosome-induced endothelial cell activation.
Authors Nazarenko I, Rana S, Baumann A, McAlear J, Hellwig A, Trendelenburg M, Lochnit G, Preissner KT, Zoller M.
Journal name CR
Publication year 2010
Sample Pancreatic cancer cells
Sample name AS-Tspan8
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density 1.14-1.17 g/mL
Molecules identified in the study Protein
mRNA
Methods used in the study RT-PCR
Western blotting
 Protein-protein interactions for Fgfbp1
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Fgfbp1 is involved
No pathways found





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