Gene description for Fgfbp1
Gene name fibroblast growth factor binding protein 1
Gene symbol Fgfbp1
Other names/aliases -
Species Rattus norvegicus
 Database cross references - Fgfbp1
ExoCarta ExoCarta_64535
Vesiclepedia VP_64535
Entrez Gene 64535
UniProt Q9QY10  
 Fgfbp1 identified in sEVs derived from the following tissue/cell type
Pancreatic cancer cells 20124479    
Pancreatic cancer cells 20124479    
 Gene ontology annotations for Fgfbp1
Molecular Function
    fibroblast growth factor binding GO:0017134 IEA
    fibroblast growth factor binding GO:0017134 ISO
    growth factor binding GO:0019838 IBA
Biological Process
    cell-cell signaling GO:0007267 IBA
    cell-cell signaling GO:0007267 IDA
    fibroblast growth factor receptor signaling pathway GO:0008543 IEA
    fibroblast growth factor receptor signaling pathway GO:0008543 ISO
    positive regulation of fibroblast growth factor receptor signaling pathway GO:0045743 IEA
    positive regulation of fibroblast growth factor receptor signaling pathway GO:0045743 ISO
    myoblast proliferation GO:0051450 IEA
    myoblast proliferation GO:0051450 ISO
    positive regulation of cell migration involved in sprouting angiogenesis GO:0090050 IEA
    positive regulation of cell migration involved in sprouting angiogenesis GO:0090050 ISO
    positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis GO:1903589 IEA
    positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis GO:1903589 ISO
    positive regulation of myoblast proliferation GO:2000288 IEA
    positive regulation of myoblast proliferation GO:2000288 ISO
Subcellular Localization
    extracellular region GO:0005576 IEA
    extracellular region GO:0005576 ISO
    plasma membrane GO:0005886 IEA
    cell surface GO:0009986 IEA
    cell surface GO:0009986 ISO
 Experiment description of studies that identified Fgfbp1 in sEVs
1
Experiment ID 92
MISEV standards
EM
Biophysical techniques
HSP70|GAPDH|CD9|CD151
Enriched markers
Negative markers
Particle analysis
Identified molecule mrna
Identification method RT-PCR
Microarray
PubMed ID 20124479    
Organism Rattus norvegicus
Experiment description Cell surface tetraspanin Tspan8 contributes to molecular pathways of exosome-induced endothelial cell activation.
Authors "Nazarenko I, Rana S, Baumann A, McAlear J, Hellwig A, Trendelenburg M, Lochnit G, Preissner KT, Zoller M."
Journal name CR
Publication year 2010
Sample Pancreatic cancer cells
Sample name AS
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density 1.14-1.17 g/mL
Molecules identified in the study Protein
mRNA
Methods used in the study RT-PCR
Western blotting
RatRef-12 Microarray
FACS
Mass spectrometry [MALDI TOF]
2
Experiment ID 93
MISEV standards
EM
Biophysical techniques
HSP70|GAPDH|CD9|CD151
Enriched markers
Negative markers
Particle analysis
Identified molecule mrna
Identification method RT-PCR
Microarray
PubMed ID 20124479    
Organism Rattus norvegicus
Experiment description Cell surface tetraspanin Tspan8 contributes to molecular pathways of exosome-induced endothelial cell activation.
Authors "Nazarenko I, Rana S, Baumann A, McAlear J, Hellwig A, Trendelenburg M, Lochnit G, Preissner KT, Zoller M."
Journal name CR
Publication year 2010
Sample Pancreatic cancer cells
Sample name AS-Tspan8
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density 1.14-1.17 g/mL
Molecules identified in the study Protein
mRNA
Methods used in the study RT-PCR
Western blotting
 Protein-protein interactions for Fgfbp1
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.



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