Gene description for Ap3m2
Gene name adaptor-related protein complex 3, mu 2 subunit
Gene symbol Ap3m2
Other names/aliases 5830445E16Rik
AP-3B
Species Mus musculus
 Database cross references - Ap3m2
ExoCarta ExoCarta_64933
Vesiclepedia VP_64933
Entrez Gene 64933
UniProt Q8R2R9  
 Ap3m2 identified in exosomes derived from the following tissue/cell type
Colon cancer cells 37309723    
T-cell lymphoma cells 37309723    
 Gene ontology annotations for Ap3m2
Biological Process
    protein transport GO:0015031 IEA
    anterograde axon cargo transport GO:0008089 IMP
    transport GO:0006810 IEA
    vesicle-mediated transport GO:0016192 IEA
    intracellular protein transport GO:0006886 IEA
    anterograde synaptic vesicle transport GO:0048490 IMP
Subcellular Localization
    Golgi apparatus GO:0005794 IEA
    membrane GO:0016020 IEA
    cytoplasmic vesicle GO:0031410 IEA
    cell GO:0005623 IMP
    intracellular GO:0005622 IMP
    clathrin adaptor complex GO:0030131 IEA
 Experiment description of studies that identified Ap3m2 in exosomes
1
Experiment ID 907
MISEV standards
✔
EM
EV Biophysical techniques
✔
Tsg101|Sdcbp|Cd151|Gapdh|Lamp2|Cd81|Cd82|Cd9|Cd63|Cd80|Flot2|Tfrc|Rab35|Rab5a
EV Enriched markers
✔
HSPA5
EV Negative markers
✔
NTA
EV Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 37309723    
Organism Mus musculus
Experiment description Proteomic analysis of the small extracellular vesicles and soluble secretory proteins from cachexia inducing and non-inducing cancer cells
Authors Chitti SV, Kang T, Fonseka P, Marzan AL, Stewart S, Shahi S, Bramich K, Ang CS, Pathan M, Gummadi S, Mathivanan S.
Journal name Proteomics
Publication year 2023
Sample Colon cancer cells
Sample name C26
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
2
Experiment ID 908
MISEV standards
✔
EM
EV Biophysical techniques
✔
Tsg101|Sdcbp|Cd151|Gapdh|Lamp2|Cd81|Cd82|Cd9|Cd63|Cd80|Flot2|Tfrc|Rab35|Rab5a
EV Enriched markers
✔
HSPA5
EV Negative markers
✔
NTA
EV Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 37309723    
Organism Mus musculus
Experiment description Proteomic analysis of the small extracellular vesicles and soluble secretory proteins from cachexia inducing and non-inducing cancer cells
Authors Chitti SV, Kang T, Fonseka P, Marzan AL, Stewart S, Shahi S, Bramich K, Ang CS, Pathan M, Gummadi S, Mathivanan S.
Journal name Proteomics
Publication year 2023
Sample T-cell lymphoma cells
Sample name EL4
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
 Protein-protein interactions for Ap3m2
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Ap3m2 is involved
No pathways found





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