Gene description for Sfxn3
Gene name sideroflexin 3
Gene symbol Sfxn3
Other names/aliases TCC
Species Rattus norvegicus
 Database cross references - Sfxn3
ExoCarta ExoCarta_65042
Entrez Gene 65042
UniProt Q9JHY2  
 Sfxn3 identified in exosomes derived from the following tissue/cell type
Reticulocytes 21828046    
 Gene ontology annotations for Sfxn3
Molecular Function
    molecular_function GO:0003674 ND
    tricarboxylate secondary active transmembrane transporter activity GO:0005371 TAS
Biological Process
    biological_process GO:0008150 ND
    iron ion homeostasis GO:0055072 IEA
    tricarboxylic acid transmembrane transport GO:0035674 TAS
Subcellular Localization
    mitochondrion GO:0005739 TAS
    mitochondrial membrane GO:0031966 IDA
    integral component of membrane GO:0016021 IEA
 Experiment description of studies that identified Sfxn3 in exosomes
1
Experiment ID 90
ISEV standards
EM
EV Biophysical techniques
HSC70|HSP90|TSG101
EV Cytosolic markers
MHCI
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry [Orbitrap]
PubMed ID 21828046    
Organism Rattus norvegicus
Experiment description The proteo-lipidic composition of exosomes changes during reticulocyte maturation.
Authors Carayon K, Chaoui K, Ronzier E, Lazar I, Bertrand-Michel J, Roques V, Balor S, Terce F, Lopez A, Salome L, Joly E
Journal name JBC
Publication year 2011
Sample Reticulocytes
Sample name Reticulocytes - D2 Rep 1
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.16-1.21 g/mL
Molecules identified in the study Protein
Lipids
Methods used in the study Mass spectrometry [QSTAR]
Mass spectrometry [Orbitrap]
Western blotting
 Protein-protein interactions for Sfxn3
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Sfxn3 is involved
No pathways found





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