Gene description for Adrm1
Gene name adhesion regulating molecule 1
Gene symbol Adrm1
Other names/aliases Gp110
Species Rattus norvegicus
 Database cross references - Adrm1
ExoCarta ExoCarta_65138
Entrez Gene 65138
UniProt Q9JMB5  
 Adrm1 identified in exosomes derived from the following tissue/cell type
Reticulocytes 21828046    
 Gene ontology annotations for Adrm1
Molecular Function
    proteasome binding GO:0070628 ISO
    protease binding GO:0002020 ISO
    endopeptidase activator activity GO:0061133 ISS
Biological Process
    follicle-stimulating hormone signaling pathway GO:0042699 ISO
    transcription elongation from RNA polymerase II promoter GO:0006368 ISO
    spermatid development GO:0007286 ISO
    ovarian follicle development GO:0001541 ISO
    positive regulation of endopeptidase activity GO:0010950 ISO
    seminiferous tubule development GO:0072520 ISO
    Sertoli cell development GO:0060009 ISO
    oogenesis GO:0048477 ISO
    adipose tissue development GO:0060612 ISO
    regulation of T cell differentiation in thymus GO:0033081 ISO
    proteasome assembly GO:0043248 ISS
    thymus development GO:0048538 ISO
    positive regulation of growth hormone receptor signaling pathway GO:0060399 ISO
Subcellular Localization
    proteasome complex GO:0000502 ISS
    plasma membrane GO:0005886 ISO
    nucleoplasm GO:0005654 ISO
    cytoplasm GO:0005737 ISO
 Experiment description of studies that identified Adrm1 in exosomes
1
Experiment ID 95
ISEV standards
EM
EV Biophysical techniques
TSG101|HSP90|HSC70
EV Cytosolic markers
MHCI
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry [Orbitrap]
PubMed ID 21828046    
Organism Rattus norvegicus
Experiment description The proteo-lipidic composition of exosomes changes during reticulocyte maturation.
Authors Carayon K, Chaoui K, Ronzier E, Lazar I, Bertrand-Michel J, Roques V, Balor S, Terce F, Lopez A, Salome L, Joly E.
Journal name JBC
Publication year 2011
Sample Reticulocytes
Sample name Reticulocytes - D7 Rep 1
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.25 g/mL
Molecules identified in the study Protein
Lipids
Methods used in the study Mass spectrometry [QSTAR]
Mass spectrometry [Orbitrap]
Western blotting
 Protein-protein interactions for Adrm1
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Adrm1 is involved
No pathways found





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