Gene description for Aldh3a2
Gene name aldehyde dehydrogenase 3 family, member A2
Gene symbol Aldh3a2
Other names/aliases Aldh4
FALDH
Species Rattus norvegicus
 Database cross references - Aldh3a2
ExoCarta ExoCarta_65183
Vesiclepedia VP_65183
Entrez Gene 65183
UniProt P30839  
 Aldh3a2 identified in sEVs derived from the following tissue/cell type
Adipocytes 25998041    
Hepatocytes 19367702    
 Gene ontology annotations for Aldh3a2
Molecular Function
    3-chloroallyl aldehyde dehydrogenase activity GO:0004028 IBA
    3-chloroallyl aldehyde dehydrogenase activity GO:0004028 IDA
    aldehyde dehydrogenase (NAD+) activity GO:0004029 IBA
    aldehyde dehydrogenase (NAD+) activity GO:0004029 ISO
    oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor GO:0016620 IEA
    protein homodimerization activity GO:0042803 IEA
    protein homodimerization activity GO:0042803 ISO
    long-chain-alcohol oxidase activity GO:0046577 IEA
    long-chain-alcohol oxidase activity GO:0046577 ISO
    long-chain fatty aldehyde dehydrogenase (NAD+) activity GO:0050061 IEA
    long-chain fatty aldehyde dehydrogenase (NAD+) activity GO:0050061 ISO
    long-chain fatty aldehyde dehydrogenase (NAD+) activity GO:0050061 ISS
    medium-chain fatty aldehyde dehydrogenase (NAD+) activity GO:0052814 IEA
    medium-chain fatty aldehyde dehydrogenase (NAD+) activity GO:0052814 ISO
    medium-chain fatty aldehyde dehydrogenase (NAD+) activity GO:0052814 ISS
Biological Process
    response to reactive oxygen species GO:0000302 IDA
    aldehyde metabolic process GO:0006081 IBA
    aldehyde metabolic process GO:0006081 IEA
    aldehyde metabolic process GO:0006081 ISO
    fatty acid metabolic process GO:0006631 IEA
    sesquiterpenoid metabolic process GO:0006714 ISO
    central nervous system development GO:0007417 IEA
    central nervous system development GO:0007417 ISO
    peripheral nervous system development GO:0007422 IEA
    peripheral nervous system development GO:0007422 ISO
    epidermis development GO:0008544 IEA
    epidermis development GO:0008544 ISO
    phytol metabolic process GO:0033306 IEA
    phytol metabolic process GO:0033306 ISO
    formaldehyde metabolic process GO:0046292 IDA
    hexadecanal metabolic process GO:0046458 IEA
    hexadecanal metabolic process GO:0046458 ISO
    hexadecanal metabolic process GO:0046458 ISS
Subcellular Localization
    cytoplasm GO:0005737 IBA
    peroxisome GO:0005777 ISO
    endoplasmic reticulum GO:0005783 IDA
    endoplasmic reticulum GO:0005783 ISO
    endoplasmic reticulum membrane GO:0005789 IDA
    endoplasmic reticulum membrane GO:0005789 IEA
    membrane GO:0016020 ISO
    intracellular membrane-bounded organelle GO:0043231 ISO
 Experiment description of studies that identified Aldh3a2 in sEVs
1
Experiment ID 225
MISEV standards
EM
Biophysical techniques
GAPDH|CD63
Enriched markers
Negative markers
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25998041    
Organism Rattus norvegicus
Experiment description Proteomic Analysis of Extracellular Vesicles Released by Adipocytes of Otsuka Long-Evans Tokushima Fatty (OLETF) Rats.
Authors "Lee JE, Moon PG, Lee IK, Baek MC"
Journal name Protein J
Publication year 2015
Sample Adipocytes
Sample name Adipocytes
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
2
Experiment ID 225
MISEV standards
EM
Biophysical techniques
GAPDH|CD63
Enriched markers
Negative markers
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25998041    
Organism Rattus norvegicus
Experiment description Proteomic Analysis of Extracellular Vesicles Released by Adipocytes of Otsuka Long-Evans Tokushima Fatty (OLETF) Rats.
Authors "Lee JE, Moon PG, Lee IK, Baek MC"
Journal name Protein J
Publication year 2015
Sample Adipocytes
Sample name Adipocytes
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
3
Experiment ID 35
MISEV standards
CEM
Biophysical techniques
TSG101|Alix|CD81|CD63
Enriched markers
HSPA5
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19367702    
Organism Rattus norvegicus
Experiment description Characterization and Comprehensive Proteome Profiling of Exosomes Secreted by Hepatocytes.
Authors "Conde-Vancells J, Rodriguez-Suarez E, Embade N, Gil D, Matthiesen R, Valle M, Elortza F, Lu SC, Mato JM, Falcon-Perez JM"
Journal name JPR
Publication year 2008
Sample Hepatocytes
Sample name Hepatocytes
Isolation/purification methods Differential centrifugation
Filtration
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [QTOF]
Western blotting
 Protein-protein interactions for Aldh3a2
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.



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