Gene description for Aldh3a2
Gene name aldehyde dehydrogenase 3 family, member A2
Gene symbol Aldh3a2
Other names/aliases Aldh4
FALDH
Species Rattus norvegicus
 Database cross references - Aldh3a2
ExoCarta ExoCarta_65183
Entrez Gene 65183
UniProt P30839  
 Aldh3a2 identified in exosomes derived from the following tissue/cell type
Adipocytes 25998041    
Hepatocytes 19367702    
 Gene ontology annotations for Aldh3a2
Molecular Function
    aldehyde dehydrogenase (NAD) activity GO:0004029 ISO
    medium-chain-aldehyde dehydrogenase activity GO:0052814 ISO
    aldehyde dehydrogenase [NAD(P)+] activity GO:0004030 IEA
    long-chain-aldehyde dehydrogenase activity GO:0050061 ISO
    long-chain-alcohol oxidase activity GO:0046577 ISO
    3-chloroallyl aldehyde dehydrogenase activity GO:0004028 IDA
Biological Process
    epidermis development GO:0008544 ISO
    phytol metabolic process GO:0033306 ISO
    oxidation-reduction process GO:0055114 ISO
    response to reactive oxygen species GO:0000302 IDA
    formaldehyde metabolic process GO:0046292 IDA
    cellular aldehyde metabolic process GO:0006081 ISO
    sesquiterpenoid metabolic process GO:0006714 ISO
    peripheral nervous system development GO:0007422 ISO
    central nervous system development GO:0007417 ISO
Subcellular Localization
    extrinsic component of endoplasmic reticulum membrane GO:0042406 IDA
    mitochondrial inner membrane GO:0005743 ISO
    endoplasmic reticulum GO:0005783 ISO
    intracellular membrane-bounded organelle GO:0043231 ISO
    peroxisome GO:0005777 ISO
    nucleus GO:0005634 IDA
    mitochondrion GO:0005739 ISO
    extracellular exosome GO:0070062 ISO
    integral component of membrane GO:0016021 IEA
    cytosol GO:0005829 IDA
 Experiment description of studies that identified Aldh3a2 in exosomes
1
Experiment ID 225
ISEV standards
EM
EV Biophysical techniques
GAPDH
EV Cytosolic markers
CD63
EV Membrane markers
EV Negative markers
NTA
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25998041    
Organism Rattus norvegicus
Experiment description Proteomic Analysis of Extracellular Vesicles Released by Adipocytes of Otsuka Long-Evans Tokushima Fatty (OLETF) Rats.
Authors Lee JE, Moon PG, Lee IK, Baek MC
Journal name Protein J
Publication year 2015
Sample Adipocytes
Sample name Adipocytes
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
2
Experiment ID 225
ISEV standards
EM
EV Biophysical techniques
GAPDH
EV Cytosolic markers
CD63
EV Membrane markers
EV Negative markers
NTA
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25998041    
Organism Rattus norvegicus
Experiment description Proteomic Analysis of Extracellular Vesicles Released by Adipocytes of Otsuka Long-Evans Tokushima Fatty (OLETF) Rats.
Authors Lee JE, Moon PG, Lee IK, Baek MC
Journal name Protein J
Publication year 2015
Sample Adipocytes
Sample name Adipocytes
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
3
Experiment ID 35
ISEV standards
CEM
EV Biophysical techniques
TSG101|Alix
EV Cytosolic markers
CD81|CD63
EV Membrane markers
HSPA5
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19367702    
Organism Rattus norvegicus
Experiment description Characterization and Comprehensive Proteome Profiling of Exosomes Secreted by Hepatocytes.
Authors Conde-Vancells J, Rodriguez-Suarez E, Embade N, Gil D, Matthiesen R, Valle M, Elortza F, Lu SC, Mato JM, Falcon-Perez JM
Journal name JPR
Publication year 2008
Sample Hepatocytes
Sample name Hepatocytes
Isolation/purification methods Differential centrifugation
Filtration
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [QTOF]
Western blotting
 Protein-protein interactions for Aldh3a2
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Aldh3a2 is involved
No pathways found





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