Gene description for Slc29a2
Gene name solute carrier family 29 (equilibrative nucleoside transporter), member 2
Gene symbol Slc29a2
Other names/aliases -
Species Rattus norvegicus
 Database cross references - Slc29a2
ExoCarta ExoCarta_65194
Vesiclepedia VP_65194
Entrez Gene 65194
UniProt O54699  
 Slc29a2 identified in sEVs derived from the following tissue/cell type
Reticulocytes 21828046    
 Gene ontology annotations for Slc29a2
Molecular Function
    neurotransmitter transmembrane transporter activity GO:0005326 IEA
    neurotransmitter transmembrane transporter activity GO:0005326 ISO
    nucleoside transmembrane transporter activity GO:0005337 IBA
    nucleoside transmembrane transporter activity GO:0005337 IDA
    nucleoside transmembrane transporter activity GO:0005337 ISO
    nucleobase transmembrane transporter activity GO:0015205 IDA
    nucleobase transmembrane transporter activity GO:0015205 ISO
    nucleobase transmembrane transporter activity GO:0015205 ISS
    adenine transmembrane transporter activity GO:0015207 IEA
    adenine transmembrane transporter activity GO:0015207 ISO
    adenine transmembrane transporter activity GO:0015207 ISS
    guanine transmembrane transporter activity GO:0015208 IEA
    guanine transmembrane transporter activity GO:0015208 ISO
    guanine transmembrane transporter activity GO:0015208 ISS
    uracil transmembrane transporter activity GO:0015210 IEA
    uracil transmembrane transporter activity GO:0015210 ISO
    uracil transmembrane transporter activity GO:0015210 ISS
    purine nucleoside transmembrane transporter activity GO:0015211 IEA
    purine nucleoside transmembrane transporter activity GO:0015211 ISO
    cytidine transmembrane transporter activity GO:0015212 IEA
    cytidine transmembrane transporter activity GO:0015212 ISO
    cytidine transmembrane transporter activity GO:0015212 ISS
    uridine transmembrane transporter activity GO:0015213 IDA
    uridine transmembrane transporter activity GO:0015213 IEA
    uridine transmembrane transporter activity GO:0015213 ISO
    uridine transmembrane transporter activity GO:0015213 ISS
Biological Process
    neurotransmitter uptake GO:0001504 IEA
    neurotransmitter uptake GO:0001504 ISO
    neurotransmitter transport GO:0006836 ISO
    lactation GO:0007595 IEP
    nucleobase transport GO:0015851 IDA
    nucleobase transport GO:0015851 ISO
    adenine transport GO:0015853 IBA
    adenine transport GO:0015853 IDA
    adenine transport GO:0015853 IEA
    adenine transport GO:0015853 ISO
    guanine transport GO:0015854 IBA
    guanine transport GO:0015854 IMP
    nucleoside transport GO:0015858 IDA
    nucleoside transport GO:0015858 ISO
    nucleoside transport GO:0015858 ISO
    purine nucleoside transmembrane transport GO:0015860 IEA
    purine nucleoside transmembrane transport GO:0015860 ISO
    cytidine transport GO:0015861 IEA
    cytidine transport GO:0015861 ISO
    cytidine transport GO:0015861 ISS
    uridine transmembrane transport GO:0015862 IBA
    uridine transmembrane transport GO:0015862 IDA
    uridine transmembrane transport GO:0015862 IEA
    uridine transmembrane transport GO:0015862 IMP
    uridine transmembrane transport GO:0015862 ISO
    uridine transmembrane transport GO:0015862 ISS
    adenosine transport GO:0032238 IDA
    adenosine transport GO:0032238 IEA
    adenosine transport GO:0032238 ISO
    adenosine transport GO:0032238 ISS
    cellular response to insulin stimulus GO:0032869 IEP
    inosine transport GO:0035340 IEA
    inosine transport GO:0035340 ISO
    inosine transport GO:0035340 ISS
    hypoxanthine transport GO:0035344 IBA
    hypoxanthine transport GO:0035344 IDA
    hypoxanthine transport GO:0035344 IEA
    hypoxanthine transport GO:0035344 IMP
    hypoxanthine transport GO:0035344 ISO
    hypoxanthine transport GO:0035344 ISS
    thymine transport GO:0035364 IBA
    thymine transport GO:0035364 IDA
    thymine transport GO:0035364 IEA
    thymine transport GO:0035364 ISO
    pyrimidine-containing compound transmembrane transport GO:0072531 ISO
    nucleoside transmembrane transport GO:1901642 IDA
    nucleoside transmembrane transport GO:1901642 ISO
    guanine transmembrane transport GO:1903716 IEA
    guanine transmembrane transport GO:1903716 ISO
    guanine transmembrane transport GO:1903716 ISS
    uracil transmembrane transport GO:1903791 IEA
    uracil transmembrane transport GO:1903791 ISO
    uracil transmembrane transport GO:1903791 ISS
    purine nucleobase transmembrane transport GO:1904823 ISO
    purine nucleobase transmembrane transport GO:1904823 ISS
Subcellular Localization
    plasma membrane GO:0005886 IBA
    plasma membrane GO:0005886 ISO
    basolateral plasma membrane GO:0016323 IBA
    basolateral plasma membrane GO:0016323 IEA
    basolateral plasma membrane GO:0016323 ISO
    apical plasma membrane GO:0016324 IDA
    apical plasma membrane GO:0016324 IEA
    apical plasma membrane GO:0016324 ISO
 Experiment description of studies that identified Slc29a2 in sEVs
1
Experiment ID 90
MISEV standards
EM
Biophysical techniques
HSC70|HSP90|TSG101|MHCI
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry [Orbitrap]
PubMed ID 21828046    
Organism Rattus norvegicus
Experiment description The proteo-lipidic composition of exosomes changes during reticulocyte maturation.
Authors "Carayon K, Chaoui K, Ronzier E, Lazar I, Bertrand-Michel J, Roques V, Balor S, Terce F, Lopez A, Salome L, Joly E"
Journal name JBC
Publication year 2011
Sample Reticulocytes
Sample name Reticulocytes - D2 Rep 1
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.16-1.21 g/mL
Molecules identified in the study Protein
Lipids
Methods used in the study Mass spectrometry [QSTAR]
Mass spectrometry [Orbitrap]
Western blotting
 Protein-protein interactions for Slc29a2
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.



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