Gene description for Slc29a2
Gene name solute carrier family 29 (equilibrative nucleoside transporter), member 2
Gene symbol Slc29a2
Other names/aliases -
Species Rattus norvegicus
 Database cross references - Slc29a2
ExoCarta ExoCarta_65194
Entrez Gene 65194
UniProt O54699  
 Slc29a2 identified in exosomes derived from the following tissue/cell type
Reticulocytes 21828046    
 Gene ontology annotations for Slc29a2
Molecular Function
    nucleoside transmembrane transporter activity GO:0005337 ISO
Biological Process
    adenine transport GO:0015853 IDA
    thymine transport GO:0035364 IDA
    nucleoside transport GO:0015858 ISO
    nucleoside transmembrane transport GO:1901642 ISO
    cellular response to insulin stimulus GO:0032869 IEP
    guanine transport GO:0015854 IMP
    hypoxanthine transport GO:0035344 IMP
    uridine transport GO:0015862 IMP
    lactation GO:0007595 IEP
Subcellular Localization
    integral component of plasma membrane GO:0005887 IEA
    cellular_component GO:0005575 ND
    basolateral plasma membrane GO:0016323 ISO
 Experiment description of studies that identified Slc29a2 in exosomes
1
Experiment ID 90
ISEV standards
✔
EM
EV Biophysical techniques
✔
HSC70|HSP90|TSG101
EV Cytosolic markers
✔
MHCI
EV Membrane markers
✘ EV Negative markers
✘ EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry [Orbitrap]
PubMed ID 21828046    
Organism Rattus norvegicus
Experiment description The proteo-lipidic composition of exosomes changes during reticulocyte maturation.
Authors Carayon K, Chaoui K, Ronzier E, Lazar I, Bertrand-Michel J, Roques V, Balor S, Terce F, Lopez A, Salome L, Joly E
Journal name JBC
Publication year 2011
Sample Reticulocytes
Sample name Reticulocytes - D2 Rep 1
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.16-1.21 g/mL
Molecules identified in the study Protein
Lipids
Methods used in the study Mass spectrometry [QSTAR]
Mass spectrometry [Orbitrap]
Western blotting
 Protein-protein interactions for Slc29a2
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Slc29a2 is involved
PathwayEvidenceSource
Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane IEA Reactome





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