Gene description for Dpysl5
Gene name dihydropyrimidinase-like 5
Gene symbol Dpysl5
Other names/aliases Crmp5
Ulip6
Species Rattus norvegicus
 Database cross references - Dpysl5
ExoCarta ExoCarta_65208
Entrez Gene 65208
UniProt Q9JHU0  
 Dpysl5 identified in exosomes derived from the following tissue/cell type
Reticulocytes 21828046    
 Gene ontology annotations for Dpysl5
Molecular Function
    microtubule binding GO:0008017 IEA
    protein binding GO:0005515 IPI
    hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds GO:0016810 IEA
Biological Process
    axon guidance GO:0007411 IEA
    neuron differentiation GO:0030182 IEP
    metabolic process GO:0008152 IEA
Subcellular Localization
    protein complex GO:0043234 IDA
    cytoplasm GO:0005737 IEA
 Experiment description of studies that identified Dpysl5 in exosomes
1
Experiment ID 90
ISEV standards
EM
EV Biophysical techniques
HSC70|HSP90|TSG101
EV Cytosolic markers
MHCI
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry [Orbitrap]
PubMed ID 21828046    
Organism Rattus norvegicus
Experiment description The proteo-lipidic composition of exosomes changes during reticulocyte maturation.
Authors Carayon K, Chaoui K, Ronzier E, Lazar I, Bertrand-Michel J, Roques V, Balor S, Terce F, Lopez A, Salome L, Joly E
Journal name JBC
Publication year 2011
Sample Reticulocytes
Sample name Reticulocytes - D2 Rep 1
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.16-1.21 g/mL
Molecules identified in the study Protein
Lipids
Methods used in the study Mass spectrometry [QSTAR]
Mass spectrometry [Orbitrap]
Western blotting
 Protein-protein interactions for Dpysl5
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Dpysl5 is involved
PathwayEvidenceSource
CRMPs in Sema3A signaling IEA Reactome





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