Gene description for Dpysl5
Gene name dihydropyrimidinase-like 5
Gene symbol Dpysl5
Other names/aliases Crmp5
Ulip6
Species Rattus norvegicus
 Database cross references - Dpysl5
ExoCarta ExoCarta_65208
Vesiclepedia VP_65208
Entrez Gene 65208
UniProt Q9JHU0  
 Dpysl5 identified in sEVs derived from the following tissue/cell type
Reticulocytes 21828046    
 Gene ontology annotations for Dpysl5
Molecular Function
    dihydropyrimidinase activity GO:0004157 IBA
    protein binding GO:0005515 IPI
    hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides GO:0016812 IBA
Biological Process
    pyrimidine nucleobase catabolic process GO:0006208 IBA
    neuron differentiation GO:0030182 IEP
    negative regulation of dendrite morphogenesis GO:0050774 ISO
Subcellular Localization
    cytoplasm GO:0005737 ISO
    cytosol GO:0005829 IBA
    dendrite GO:0030425 ISO
    protein-containing complex GO:0032991 IDA
    neuronal cell body GO:0043025 ISO
    synapse GO:0045202 ISO
    glutamatergic synapse GO:0098978 ISO
 Experiment description of studies that identified Dpysl5 in sEVs
1
Experiment ID 90
MISEV standards
✔
EM
Biophysical techniques
✔
HSC70|HSP90|TSG101|MHCI
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry [Orbitrap]
PubMed ID 21828046    
Organism Rattus norvegicus
Experiment description The proteo-lipidic composition of exosomes changes during reticulocyte maturation.
Authors "Carayon K, Chaoui K, Ronzier E, Lazar I, Bertrand-Michel J, Roques V, Balor S, Terce F, Lopez A, Salome L, Joly E"
Journal name JBC
Publication year 2011
Sample Reticulocytes
Sample name Reticulocytes - D2 Rep 1
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.16-1.21 g/mL
Molecules identified in the study Protein
Lipids
Methods used in the study Mass spectrometry [QSTAR]
Mass spectrometry [Orbitrap]
Western blotting
 Protein-protein interactions for Dpysl5
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.



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