Gene description for Myo1c
Gene name myosin IC
Gene symbol Myo1c
Other names/aliases Myr2
Species Rattus norvegicus
 Database cross references - Myo1c
ExoCarta ExoCarta_65261
Entrez Gene 65261
UniProt Q63355  
 Myo1c identified in exosomes derived from the following tissue/cell type
Adipocytes 25998041    
 Gene ontology annotations for Myo1c
Molecular Function
    calmodulin binding GO:0005516 IEA
    Ral GTPase binding GO:0017160 ISO
    motor activity GO:0003774 IEA
    receptor binding GO:0005102 ISO
    ATP binding GO:0005524 IEA
    actin binding GO:0003779 IEA
    actin-dependent ATPase activity GO:0030898 IDA
    protein C-terminus binding GO:0008022 ISO
Biological Process
    transport GO:0006810 ISO
    protein targeting GO:0006605 ISO
    metabolic process GO:0008152 IEA
    regulation of bicellular tight junction assembly GO:2000810 ISO
    positive regulation of protein targeting to membrane GO:0090314 ISO
    positive regulation of vascular endothelial growth factor signaling pathway GO:1900748 ISO
    protein targeting to membrane GO:0006612 ISO
    positive regulation of cell migration by vascular endothelial growth factor signaling pathway GO:0038089 ISO
    positive regulation of cell migration GO:0030335 ISO
Subcellular Localization
    brush border GO:0005903 ISO
    filamentous actin GO:0031941 ISO
    lateral plasma membrane GO:0016328 ISO
    extracellular exosome GO:0070062 ISO
    membrane raft GO:0045121 ISO
    stereocilium membrane GO:0060171 IEA
    mitochondrion GO:0005739 ISO
    stereocilium GO:0032420 ISO
    plasma membrane GO:0005886 ISO
    myosin I complex GO:0045160 ISO
    stress fiber GO:0001725 ISO
    ruffle GO:0001726 IEA
    cytoplasmic membrane-bounded vesicle GO:0016023 IEA
    cytoplasm GO:0005737 ISO
    microvillus GO:0005902 ISO
    nucleus GO:0005634 IDA
    basal plasma membrane GO:0009925 ISO
    membrane GO:0016020 ISO
    nucleoplasm GO:0005654 ISO
 Experiment description of studies that identified Myo1c in exosomes
1
Experiment ID 225
ISEV standards
EM
EV Biophysical techniques
GAPDH
EV Cytosolic markers
CD63
EV Membrane markers
EV Negative markers
NTA
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25998041    
Organism Rattus norvegicus
Experiment description Proteomic Analysis of Extracellular Vesicles Released by Adipocytes of Otsuka Long-Evans Tokushima Fatty (OLETF) Rats.
Authors Lee JE, Moon PG, Lee IK, Baek MC
Journal name Protein J
Publication year 2015
Sample Adipocytes
Sample name Adipocytes
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
 Protein-protein interactions for Myo1c
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.



Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here