Gene description for Tmem176a
Gene name transmembrane protein 176A
Gene symbol Tmem176a
Other names/aliases 0610011I04Rik
AU040201
AU041743
Keg2
Species Mus musculus
 Database cross references - Tmem176a
ExoCarta ExoCarta_66058
Entrez Gene 66058
UniProt Q9DCS1  
 Tmem176a identified in exosomes derived from the following tissue/cell type
Mast cells 17486113    
 Gene ontology annotations for Tmem176a
Molecular Function
    protein binding GO:0005515 IPI
Biological Process
    negative regulation of dendritic cell differentiation GO:2001199 IMP
Subcellular Localization
    membrane GO:0016020 IEA
    integral component of membrane GO:0016021 IEA
 Experiment description of studies that identified Tmem176a in exosomes
1
Experiment ID 15
ISEV standards
EM
EV Biophysical techniques
EV Cytosolic markers
CD63
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 17486113    
Organism Mus musculus
Homo sapiens
Experiment description Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Authors Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO
Journal name NCB
Publication year 2007
Sample Mast cells
Sample name MC9
Bone marrow-derived mast cells
HMC-1
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.11-1.21 g/mL
Molecules identified in the study Protein
mRNA
miRNA
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
Microarray
miRCURY LNA Array
 Protein-protein interactions for Tmem176a
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Tmem176a is involved
No pathways found





Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here