Gene description for Pgls
Gene name 6-phosphogluconolactonase
Gene symbol Pgls
Other names/aliases 1110030K05Rik
AI447866
Plgs
Species Mus musculus
 Database cross references - Pgls
ExoCarta ExoCarta_66171
Entrez Gene 66171
UniProt Q9CQ60  
 Pgls identified in exosomes derived from the following tissue/cell type
Pancreatic cells 19351151    
 Gene ontology annotations for Pgls
Molecular Function
    monosaccharide binding GO:0048029 ISO
    hydrolase activity GO:0016787 IEA
    6-phosphogluconolactonase activity GO:0017057 ISO
Biological Process
    carbohydrate metabolic process GO:0005975 IEA
    pentose-phosphate shunt GO:0006098 ISO
    pentose-phosphate shunt, oxidative branch GO:0009051 ISO
Subcellular Localization
    extracellular exosome GO:0070062 ISO
    cytoplasm GO:0005737 IEA
 Experiment description of studies that identified Pgls in exosomes
1
Experiment ID 188
ISEV standards
✔
EM
EV Biophysical techniques
✔
GAPDH|UCHL1|HSP90
EV Cytosolic markers
✘ EV Membrane markers
✘ EV Negative markers
✘ EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19351151    
Organism Mus musculus
Experiment description Characterization of vesicles secreted from insulinoma NIT-1 cells.
Authors Lee HS, Jeong J, Lee KJ.
Journal name J Proteome Res
Publication year 2009
Sample Pancreatic cells
Sample name Pancreatic beta cell (NIT-1)
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for Pgls
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Pgls is involved
PathwayEvidenceSource
Pentose phosphate pathway (hexose monophosphate shunt) IEA Reactome





Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here