Gene description for Nop10
Gene name NOP10 ribonucleoprotein
Gene symbol Nop10
Other names/aliases 1110036B12Rik
NOP10P
Nola3
Species Mus musculus
 Database cross references - Nop10
ExoCarta ExoCarta_66181
Vesiclepedia VP_66181
Entrez Gene 66181
UniProt Q9CQS2  
 Nop10 identified in sEVs derived from the following tissue/cell type
Mast cells 17486113    
 Gene ontology annotations for Nop10
Molecular Function
    RNA binding GO:0003723 ISO
    protein binding GO:0005515 IPI
    box H/ACA snoRNA binding GO:0034513 IEA
    box H/ACA snoRNA binding GO:0034513 ISO
    telomerase RNA binding GO:0070034 IBA
    telomerase RNA binding GO:0070034 IEA
    telomerase RNA binding GO:0070034 ISO
Biological Process
    snoRNA guided rRNA pseudouridine synthesis GO:0000454 IEA
    snoRNA guided rRNA pseudouridine synthesis GO:0000454 ISO
    telomere maintenance via telomerase GO:0007004 ISO
    telomere maintenance via telomerase GO:0007004 ISS
    telomere maintenance via telomerase GO:0007004 NAS
    rRNA pseudouridine synthesis GO:0031118 IBA
    snRNA pseudouridine synthesis GO:0031120 IBA
Subcellular Localization
    telomerase holoenzyme complex GO:0005697 ISO
    telomerase holoenzyme complex GO:0005697 ISS
    telomerase holoenzyme complex GO:0005697 NAS
    Cajal body GO:0015030 IEA
    nuclear body GO:0016604 ISO
    box H/ACA snoRNP complex GO:0031429 IBA
    box H/ACA snoRNP complex GO:0031429 IEA
    box H/ACA snoRNP complex GO:0031429 ISO
    box H/ACA telomerase RNP complex GO:0090661 IEA
    box H/ACA telomerase RNP complex GO:0090661 ISO
 Experiment description of studies that identified Nop10 in sEVs
1
Experiment ID 15
MISEV standards
EM
Biophysical techniques
CD63
Enriched markers
Negative markers
Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 17486113    
Organism Mus musculus
Homo sapiens
Experiment description Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Authors "Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO"
Journal name NCB
Publication year 2007
Sample Mast cells
Sample name MC9
Bone marrow-derived mast cells
HMC-1
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.11-1.21 g/mL
Molecules identified in the study Protein
mRNA
miRNA
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
Microarray
miRCURY LNA Array
 Protein-protein interactions for Nop10
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 Fancd2  
Affinity Capture-MS Mus musculus
2 Eed  
Affinity Capture-MS Mus musculus
View the network image/svg+xml



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