Gene description for Ier3ip1
Gene name immediate early response 3 interacting protein 1
Gene symbol Ier3ip1
Other names/aliases 1110057H19Rik
AI644142
AL022842
AL022863
AV026606
Species Mus musculus
 Database cross references - Ier3ip1
ExoCarta ExoCarta_66191
Vesiclepedia VP_66191
Entrez Gene 66191
UniProt Q9CR20  
 Ier3ip1 identified in sEVs derived from the following tissue/cell type
Mast cells 17486113    
 Gene ontology annotations for Ier3ip1
Molecular Function
    molecular_function GO:0003674 ND
Biological Process
    positive regulation of extracellular matrix constituent secretion GO:0003331 ISO
    positive regulation of extracellular matrix constituent secretion GO:0003331 ISS
    endoplasmic reticulum to Golgi vesicle-mediated transport GO:0006888 IBA
    brain development GO:0007420 ISO
    brain development GO:0007420 ISS
    protein transport GO:0015031 IEA
    organ growth GO:0035265 ISO
    organ growth GO:0035265 ISS
    positive regulation of protein secretion GO:0050714 ISO
    positive regulation of protein secretion GO:0050714 ISS
    regulation of fibroblast apoptotic process GO:2000269 ISO
    regulation of fibroblast apoptotic process GO:2000269 ISS
Subcellular Localization
    Golgi membrane GO:0000139 IBA
    endoplasmic reticulum GO:0005783 ISO
    endoplasmic reticulum membrane GO:0005789 IBA
    endoplasmic reticulum membrane GO:0005789 ISO
    endoplasmic reticulum membrane GO:0005789 ISS
    Golgi apparatus GO:0005794 ISO
    COPII-coated ER to Golgi transport vesicle GO:0030134 IBA
 Experiment description of studies that identified Ier3ip1 in sEVs
1
Experiment ID 15
MISEV standards
EM
Biophysical techniques
CD63
Enriched markers
Negative markers
Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 17486113    
Organism Mus musculus
Homo sapiens
Experiment description Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Authors "Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO"
Journal name NCB
Publication year 2007
Sample Mast cells
Sample name MC9
Bone marrow-derived mast cells
HMC-1
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.11-1.21 g/mL
Molecules identified in the study Protein
mRNA
miRNA
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
Microarray
miRCURY LNA Array
 Protein-protein interactions for Ier3ip1
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Ier3ip1 is involved
No pathways found





Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here