Gene description for Ier3ip1
Gene name immediate early response 3 interacting protein 1
Gene symbol Ier3ip1
Other names/aliases 1110057H19Rik
AI644142
AL022842
AL022863
AV026606
Species Mus musculus
 Database cross references - Ier3ip1
ExoCarta ExoCarta_66191
Entrez Gene 66191
UniProt Q9CR20  
 Ier3ip1 identified in exosomes derived from the following tissue/cell type
Mast cells 17486113    
 Gene ontology annotations for Ier3ip1
Molecular Function
    molecular_function GO:0003674 ND
Biological Process
    regulation of fibroblast apoptotic process GO:2000269 ISO
Subcellular Localization
    endoplasmic reticulum GO:0005783 ISO
    Golgi apparatus GO:0005794 ISO
    integral component of membrane GO:0016021 IEA
    membrane GO:0016020 ISO
 Experiment description of studies that identified Ier3ip1 in exosomes
1
Experiment ID 15
ISEV standards
EM
EV Biophysical techniques
EV Cytosolic markers
CD63
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 17486113    
Organism Mus musculus
Homo sapiens
Experiment description Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Authors Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO
Journal name NCB
Publication year 2007
Sample Mast cells
Sample name MC9
Bone marrow-derived mast cells
HMC-1
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.11-1.21 g/mL
Molecules identified in the study Protein
mRNA
miRNA
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
Microarray
miRCURY LNA Array
 Protein-protein interactions for Ier3ip1
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Ier3ip1 is involved
No pathways found





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