Gene description for Pycrl
Gene name pyrroline-5-carboxylate reductase-like
Gene symbol Pycrl
Other names/aliases 1110058B13Rik
2700073G24Rik
Species Mus musculus
 Database cross references - Pycrl
ExoCarta ExoCarta_66194
Entrez Gene 66194
UniProt Q9DCC4  
 Pycrl identified in exosomes derived from the following tissue/cell type
Fibroblasts 23260141    
 Gene ontology annotations for Pycrl
Molecular Function
    protein binding GO:0005515 IPI
    cytidine deaminase activity GO:0004126 ISO
    oxidoreductase activity GO:0016491 IEA
    pyrroline-5-carboxylate reductase activity GO:0004735 IEA
    identical protein binding GO:0042802 IPI
Biological Process
    cytidine deamination GO:0009972 ISO
    oxidation-reduction process GO:0055114 IEA
    proline biosynthetic process GO:0006561 IEA
    cellular amino acid biosynthetic process GO:0008652 IEA
Subcellular Localization
    cellular_component GO:0005575 ND
 Experiment description of studies that identified Pycrl in exosomes
1
Experiment ID 210
ISEV standards
EM
EV Biophysical techniques
EV Cytosolic markers
CD81|FLOT1
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23260141    
Organism Mus musculus
Experiment description Exosomes Mediate Stromal Mobilization of Autocrine Wnt-PCP Signaling in Breast Cancer Cell Migration.
Authors Luga V, Zhang L, Viloria-Petit AM, Ogunjimi AA, Inanlou MR, Chiu E, Buchanan M, Hosein AN, Basik M, Wrana JL.
Journal name Cell
Publication year 2012
Sample Fibroblasts
Sample name Normal-Fibroblasts (L cells)
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for Pycrl
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Pycrl is involved
No pathways found





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