Gene description for Tmem126a
Gene name transmembrane protein 126A
Gene symbol Tmem126a
Other names/aliases 1810020E01Rik
Species Mus musculus
 Database cross references - Tmem126a
ExoCarta ExoCarta_66271
Entrez Gene 66271
UniProt Q9D8Y1  
 Tmem126a identified in exosomes derived from the following tissue/cell type
Neural stem cells 25242146    
 Gene ontology annotations for Tmem126a
Molecular Function
    molecular_function GO:0003674 ND
Biological Process
    optic nerve development GO:0021554 ISO
Subcellular Localization
    membrane GO:0016020 IEA
    mitochondrion GO:0005739 ISO
    mitochondrial inner membrane GO:0005743 IEA
    integral component of membrane GO:0016021 IEA
 Experiment description of studies that identified Tmem126a in exosomes
1
Experiment ID 264
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
CD63|CD9
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25242146    
Organism Mus musculus
Experiment description Extracellular Vesicles from Neural Stem Cells Transfer IFN-γ via Ifngr1 to Activate Stat1 Signaling in Target Cells
Authors Chiara Cossetti, Nunzio Iraci, Tim R. Mercer, Tommaso Leonardi, Emanuele Alpi, Denise Drago, Clara Alfaro-Cervello, Harpreet K. Saini, Matthew P. Davis, Julia Schaeffer, Beatriz Vega, Matilde Stefanini, CongJian Zhao, Werner Muller, Jose Manuel Garcia-Verdugo, Suresh Mathivanan, Angela Bachi, Anton J. Enright, John S. Mattick, Stefano Pluchino
Journal name Molecular Cell
Publication year 2014
Sample Neural stem cells
Sample name NPCs - Th2 treated
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.20 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
 Protein-protein interactions for Tmem126a
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Tmem126a is involved
No pathways found





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