Gene description for Anp32e
Gene name acidic (leucine-rich) nuclear phosphoprotein 32 family, member E
Gene symbol Anp32e
Other names/aliases 2810018A15Rik
AI047746
AI326868
CPD1
LANP-L
LANPL
mLANP-L
Species Mus musculus
 Database cross references - Anp32e
ExoCarta ExoCarta_66471
Vesiclepedia VP_66471
Entrez Gene 66471
UniProt P97822  
 Anp32e identified in sEVs derived from the following tissue/cell type
Colon cancer cells 37309723    
T-cell lymphoma cells 37309723    
 Gene ontology annotations for Anp32e
Molecular Function
    phosphatase inhibitor activity GO:0019212 IBA
    phosphatase inhibitor activity GO:0019212 IDA
    histone binding GO:0042393 IBA
    histone binding GO:0042393 ISO
    histone binding GO:0042393 ISS
    protein folding chaperone GO:0044183 ISO
    histone chaperone activity GO:0140713 ISO
    histone chaperone activity GO:0140713 ISS
Biological Process
    chromatin organization GO:0006325 IEA
    regulation of apoptotic process GO:0042981 IBA
Subcellular Localization
    Swr1 complex GO:0000812 ISO
    Swr1 complex GO:0000812 ISS
    nucleus GO:0005634 IBA
    nucleus GO:0005634 IDA
    nucleus GO:0005634 ISO
    cytoplasm GO:0005737 IDA
    synaptic vesicle membrane GO:0030672 IDA
    cytoplasmic vesicle GO:0031410 IDA
    postsynaptic density membrane GO:0098839 IDA
    postsynaptic endosome membrane GO:0098895 IDA
    glutamatergic synapse GO:0098978 IDA
 Experiment description of studies that identified Anp32e in sEVs
1
Experiment ID 907
MISEV standards
✔
EM
Biophysical techniques
✔
Tsg101|Sdcbp|Cd151|Gapdh|Lamp2|Cd81|Cd82|Cd9|Cd63|Cd80|Flot2|Tfrc|Rab35|Rab5a
Enriched markers
✔
HSPA5
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 37309723    
Organism Mus musculus
Experiment description Proteomic analysis of the small extracellular vesicles and soluble secretory proteins from cachexia inducing and non-inducing cancer cells
Authors "Chitti SV, Kang T, Fonseka P, Marzan AL, Stewart S, Shahi S, Bramich K, Ang CS, Pathan M, Gummadi S, Mathivanan S."
Journal name Proteomics
Publication year 2023
Sample Colon cancer cells
Sample name C26
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
2
Experiment ID 908
MISEV standards
✔
EM
Biophysical techniques
✔
Tsg101|Sdcbp|Cd151|Gapdh|Lamp2|Cd81|Cd82|Cd9|Cd63|Cd80|Flot2|Tfrc|Rab35|Rab5a
Enriched markers
✔
HSPA5
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 37309723    
Organism Mus musculus
Experiment description Proteomic analysis of the small extracellular vesicles and soluble secretory proteins from cachexia inducing and non-inducing cancer cells
Authors "Chitti SV, Kang T, Fonseka P, Marzan AL, Stewart S, Shahi S, Bramich K, Ang CS, Pathan M, Gummadi S, Mathivanan S."
Journal name Proteomics
Publication year 2023
Sample T-cell lymphoma cells
Sample name EL4
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
 Protein-protein interactions for Anp32e
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 Twist1  
Proximity Label-MS Mus musculus
2 Tmem173  
Proximity Label-MS Mus musculus
3 Unk  
Affinity Capture-RNA Mus musculus
View the network image/svg+xml
 Pathways in which Anp32e is involved
No pathways found





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