Gene description for Prelid1
Gene name PRELI domain containing 1
Gene symbol Prelid1
Other names/aliases 2610524G07Rik
Preli
Species Mus musculus
 Database cross references - Prelid1
ExoCarta ExoCarta_66494
Entrez Gene 66494
UniProt Q8R107  
 Prelid1 identified in exosomes derived from the following tissue/cell type
Mast cells 17486113    
 Gene ontology annotations for Prelid1
Molecular Function
    phosphatidic acid transporter activity GO:1990050 ISO
Biological Process
    phospholipid transport GO:0015914 ISO
    transport GO:0006810 IEA
    regulation of membrane lipid distribution GO:0097035 ISO
    negative regulation of release of cytochrome c from mitochondria GO:0090201 ISO
    positive regulation of endopeptidase activity GO:0010950 ISO
    regulation of T cell differentiation GO:0045580 ISO
    positive regulation of T cell apoptotic process GO:0070234 ISO
    lipid transport GO:0006869 IEA
    regulation of mitochondrial membrane potential GO:0051881 ISO
    positive regulation of phospholipid transport GO:2001140 ISO
    apoptotic process GO:0006915 IEA
    negative regulation of apoptotic process GO:0043066 ISO
    positive regulation of cellular respiration GO:1901857 ISO
    negative regulation of mitochondrial membrane potential GO:0010917 ISO
Subcellular Localization
    protein complex GO:0043234 ISO
    mitochondrial intermembrane space GO:0005758 ISO
    mitochondrion GO:0005739 ISO
    nucleoplasm GO:0005654 ISO
 Experiment description of studies that identified Prelid1 in exosomes
1
Experiment ID 15
ISEV standards
EM
EV Biophysical techniques
EV Cytosolic markers
CD63
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 17486113    
Organism Mus musculus
Homo sapiens
Experiment description Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Authors Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO
Journal name NCB
Publication year 2007
Sample Mast cells
Sample name MC9
Bone marrow-derived mast cells
HMC-1
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.11-1.21 g/mL
Molecules identified in the study Protein
mRNA
miRNA
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
Microarray
miRCURY LNA Array
 Protein-protein interactions for Prelid1
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Prelid1 is involved
No pathways found





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