Gene description for Lamtor1
Gene name	late endosomal/lysosomal adaptor, MAPK and MTOR activator 1
Gene symbol	Lamtor1
Other names/aliases	2400001E08Rik Pdro p18
Species	Mus musculus
Database cross references - Lamtor1
ExoCarta	ExoCarta_66508
Vesiclepedia	VP_66508
Entrez Gene	66508
UniProt	Q9CQ22
Lamtor1 identified in sEVs derived from the following tissue/cell type
Mast cells	17486113

Gene ontology annotations for Lamtor1

Molecular Function     guanyl-nucleotide exchange factor activity GO:0005085 IBA     guanyl-nucleotide exchange factor activity GO:0005085 ISO     guanyl-nucleotide exchange factor activity GO:0005085 ISS     protein binding GO:0005515 IPI     protein-membrane adaptor activity GO:0043495 IDA     protein-membrane adaptor activity GO:0043495 ISO     GTPase binding GO:0051020 IEA     GTPase binding GO:0051020 ISO     molecular adaptor activity GO:0060090 IBA     molecular adaptor activity GO:0060090 ISO     molecular adaptor activity GO:0060090 ISS Biological Process     regulation of cell growth GO:0001558 ISO     regulation of cell growth GO:0001558 ISS     regulation of receptor recycling GO:0001919 IBA     regulation of receptor recycling GO:0001919 IMP     endosome organization GO:0007032 IMP     lysosome organization GO:0007040 IMP     protein localization GO:0008104 IMP     protein localization GO:0008104 ISO     regulation of cholesterol efflux GO:0010874 ISO     regulation of cholesterol efflux GO:0010874 ISS     endosomal transport GO:0016197 IMP     cellular response to nutrient levels GO:0031669 IEA     cellular response to nutrient levels GO:0031669 ISO     positive regulation of TOR signaling GO:0032008 ISO     positive regulation of TOR signaling GO:0032008 ISS     lysosome localization GO:0032418 IMP     TORC1 signaling GO:0038202 NAS     cholesterol homeostasis GO:0042632 ISO     cholesterol homeostasis GO:0042632 ISS     positive regulation of MAPK cascade GO:0043410 IBA     positive regulation of MAPK cascade GO:0043410 IMP     regulation of cholesterol import GO:0060620 ISO     regulation of cholesterol import GO:0060620 ISS     cellular response to amino acid stimulus GO:0071230 IBA     cellular response to amino acid stimulus GO:0071230 ISO     cellular response to amino acid stimulus GO:0071230 ISS     protein localization to membrane GO:0072657 IDA     protein localization to membrane GO:0072657 ISO     positive regulation of protein localization to lysosome GO:0150032 IEA     positive regulation of protein localization to lysosome GO:0150032 ISO     positive regulation of TORC1 signaling GO:1904263 IDA     positive regulation of TORC1 signaling GO:1904263 ISO Subcellular Localization     lysosome GO:0005764 ISO     lysosome GO:0005764 ISS     lysosomal membrane GO:0005765 IBA     lysosomal membrane GO:0005765 IDA     lysosomal membrane GO:0005765 ISO     lysosomal membrane GO:0005765 NAS     late endosome membrane GO:0031902 ISO     late endosome membrane GO:0031902 ISS     late endosome membrane GO:0031902 NAS     membrane raft GO:0045121 ISO     membrane raft GO:0045121 ISS     Ragulator complex GO:0071986 IBA     Ragulator complex GO:0071986 ISO     Ragulator complex GO:0071986 ISS     FNIP-folliculin RagC/D GAP GO:1990877 IEA     FNIP-folliculin RagC/D GAP GO:1990877 ISO