Gene description for Tril
Gene name TLR4 interactor with leucine-rich repeats
Gene symbol Tril
Other names/aliases 1200009O22Rik
AI316813
mKIAA0644
Species Mus musculus
 Database cross references - Tril
ExoCarta ExoCarta_66873
Entrez Gene 66873
UniProt Q9DBY4  
 Tril identified in exosomes derived from the following tissue/cell type
Fibroblasts 23260141    
 Gene ontology annotations for Tril
Molecular Function
    lipopolysaccharide binding GO:0001530 ISO
Biological Process
    toll-like receptor 4 signaling pathway GO:0034142 ISO
    regulation of cytokine production involved in immune response GO:0002718 ISO
    innate immune response GO:0045087 IEA
    inflammatory response GO:0006954 IEA
    immune system process GO:0002376 IEA
Subcellular Localization
    membrane GO:0016020 IEA
    integral component of membrane GO:0016021 IEA
    lipopolysaccharide receptor complex GO:0046696 ISO
 Experiment description of studies that identified Tril in exosomes
1
Experiment ID 210
ISEV standards
EM
EV Biophysical techniques
EV Cytosolic markers
CD81|FLOT1
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23260141    
Organism Mus musculus
Experiment description Exosomes Mediate Stromal Mobilization of Autocrine Wnt-PCP Signaling in Breast Cancer Cell Migration.
Authors Luga V, Zhang L, Viloria-Petit AM, Ogunjimi AA, Inanlou MR, Chiu E, Buchanan M, Hosein AN, Basik M, Wrana JL.
Journal name Cell
Publication year 2012
Sample Fibroblasts
Sample name Normal-Fibroblasts (L cells)
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for Tril
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Tril is involved
No pathways found





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