Gene description for Naa16
Gene name N(alpha)-acetyltransferase 16, NatA auxiliary subunit
Gene symbol Naa16
Other names/aliases 1300019C06Rik
Narg1l
Species Mus musculus
 Database cross references - Naa16
ExoCarta ExoCarta_66897
Entrez Gene 66897
UniProt Q9DBB4  
 Naa16 identified in exosomes derived from the following tissue/cell type
Mast cells 17486113    
 Gene ontology annotations for Naa16
Molecular Function
    ribosome binding GO:0043022 ISO
    peptide alpha-N-acetyltransferase activity GO:0004596 ISO
Biological Process
    protein stabilization GO:0050821 ISO
    negative regulation of apoptotic process GO:0043066 ISO
    N-terminal protein amino acid acetylation GO:0006474 ISO
Subcellular Localization
    cytoplasm GO:0005737 ISO
    NatA complex GO:0031415 ISO
    extracellular exosome GO:0070062 ISO
 Experiment description of studies that identified Naa16 in exosomes
1
Experiment ID 15
ISEV standards
EM
EV Biophysical techniques
EV Cytosolic markers
CD63
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 17486113    
Organism Mus musculus
Homo sapiens
Experiment description Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Authors Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO
Journal name NCB
Publication year 2007
Sample Mast cells
Sample name MC9
Bone marrow-derived mast cells
HMC-1
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.11-1.21 g/mL
Molecules identified in the study Protein
mRNA
miRNA
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
Microarray
miRCURY LNA Array
 Protein-protein interactions for Naa16
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Naa16 is involved
No pathways found





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