Gene description for Naaa
Gene name N-acylethanolamine acid amidase
Gene symbol Naaa
Other names/aliases 2210023K21Rik
3830414F09Rik
Asahl
Species Mus musculus
 Database cross references - Naaa
ExoCarta ExoCarta_67111
Entrez Gene 67111
UniProt Q9D7V9  
 Naaa identified in exosomes derived from the following tissue/cell type
Mast cells 17486113    
 Gene ontology annotations for Naaa
Molecular Function
    isonicotinic acid hydrazide hydrolase activity GO:0034876 IEA
    N2-acetyl-L-lysine deacetylase activity GO:0043747 IEA
    histone deacetylase activity GO:0004407 IEA
    chitooligosaccharide deacetylase activity GO:0052790 IEA
    hydrolase activity GO:0016787 IEA
    transcription factor binding GO:0008134 ISO
    4'-(2-hydroxyisopropyl)phenylurea amidohydrolase activity GO:0034571 IEA
    (3,5-dichlorophenylurea)acetate amidohydrolase activity GO:0018749 IEA
    N-acetylcitrulline deacetylase activity GO:0043909 IEA
    UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity GO:0008759 IEA
    iprodione amidohydrolase activity GO:0018748 IEA
    diacetylchitobiose deacetylase activity GO:0052773 IEA
    didemethylisoproturon amidohydrolase activity GO:0034573 IEA
    N-isopropylacetanilide amidohydrolase activity GO:0034576 IEA
    cis-aconitamide amidase activity GO:0034882 IEA
    hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds GO:0016810 ISO
    protein-N-terminal asparagine amidohydrolase activity GO:0008418 IEA
    N-acetylgalactosamine-6-phosphate deacetylase activity GO:0047419 IEA
    gamma-N-formylaminovinylacetate hydrolase activity GO:0034885 IEA
    O-succinylbenzoate synthase activity GO:0043748 IEA
    N-cyclohexylformamide amidohydrolase activity GO:0034781 IEA
    indoleacetamide hydrolase activity GO:0043864 IEA
Biological Process
    lipid metabolic process GO:0006629 IEA
Subcellular Localization
    extracellular exosome GO:0070062 ISO
    cytoplasm GO:0005737 ISO
    lysosome GO:0005764 IEA
 Experiment description of studies that identified Naaa in exosomes
1
Experiment ID 15
ISEV standards
✔
EM
EV Biophysical techniques
✘ EV Cytosolic markers
✔
CD63
EV Membrane markers
✘ EV Negative markers
✘ EV Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 17486113    
Organism Mus musculus
Homo sapiens
Experiment description Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Authors Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO
Journal name NCB
Publication year 2007
Sample Mast cells
Sample name MC9
Bone marrow-derived mast cells
HMC-1
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.11-1.21 g/mL
Molecules identified in the study Protein
mRNA
miRNA
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
Microarray
miRCURY LNA Array
 Protein-protein interactions for Naaa
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Naaa is involved
No pathways found





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