Gene description for Naaa
Gene name N-acylethanolamine acid amidase
Gene symbol Naaa
Other names/aliases 2210023K21Rik
3830414F09Rik
Asahl
Species Mus musculus
 Database cross references - Naaa
ExoCarta ExoCarta_67111
Vesiclepedia VP_67111
Entrez Gene 67111
UniProt Q9D7V9  
 Naaa identified in sEVs derived from the following tissue/cell type
Mast cells 17486113    
 Gene ontology annotations for Naaa
Molecular Function
    hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds GO:0016810 IBA
    hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds GO:0016810 ISO
    N-acylsphingosine amidohydrolase activity GO:0017040 ISO
    N-acylsphingosine amidohydrolase activity GO:0017040 ISS
    fatty acid amide hydrolase activity GO:0017064 ISO
    fatty acid amide hydrolase activity GO:0017064 ISS
    N-(long-chain-acyl)ethanolamine deacylase activity GO:0047412 ISO
    N-(long-chain-acyl)ethanolamine deacylase activity GO:0047412 ISS
    DNA-binding transcription factor binding GO:0140297 IEA
    DNA-binding transcription factor binding GO:0140297 ISO
Biological Process
    fatty acid metabolic process GO:0006631 IEA
    fatty acid metabolic process GO:0006631 ISO
    fatty acid metabolic process GO:0006631 ISS
    sphingosine metabolic process GO:0006670 ISO
    sphingosine metabolic process GO:0006670 ISS
    lipid catabolic process GO:0016042 IEA
    N-acylethanolamine metabolic process GO:0070291 ISO
    N-acylethanolamine metabolic process GO:0070291 ISS
    N-acylphosphatidylethanolamine metabolic process GO:0070292 ISO
    N-acylphosphatidylethanolamine metabolic process GO:0070292 ISS
Subcellular Localization
    cytoplasm GO:0005737 ISO
    lysosome GO:0005764 IDA
    lysosome GO:0005764 ISO
    lysosome GO:0005764 ISS
    membrane GO:0016020 ISO
    membrane GO:0016020 ISS
 Experiment description of studies that identified Naaa in sEVs
1
Experiment ID 15
MISEV standards
EM
Biophysical techniques
CD63
Enriched markers
Negative markers
Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 17486113    
Organism Mus musculus
Homo sapiens
Experiment description Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Authors "Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO"
Journal name NCB
Publication year 2007
Sample Mast cells
Sample name MC9
Bone marrow-derived mast cells
HMC-1
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.11-1.21 g/mL
Molecules identified in the study Protein
mRNA
miRNA
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
Microarray
miRCURY LNA Array
 Protein-protein interactions for Naaa
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Naaa is involved
PathwayEvidenceSource
Neuronal System IEA Reactome
Neurotransmitter release cycle IEA Reactome
Transmission across Chemical Synapses IEA Reactome





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