Gene description for Lpar6
Gene name lysophosphatidic acid receptor 6
Gene symbol Lpar6
Other names/aliases 2610302I02Rik
P2ry5
P2y5
Species Mus musculus
 Database cross references - Lpar6
ExoCarta ExoCarta_67168
Entrez Gene 67168
UniProt Q8BMC0  
 Lpar6 identified in exosomes derived from the following tissue/cell type
Mast cells 17486113    
 Gene ontology annotations for Lpar6
Molecular Function
    G-protein coupled receptor activity GO:0004930 IEA
    signal transducer activity GO:0004871 IEA
    molecular_function GO:0003674 ND
Biological Process
    biological_process GO:0008150 ND
    signal transduction GO:0007165 IEA
    G-protein coupled receptor signaling pathway GO:0007186 IEA
Subcellular Localization
    integral component of membrane GO:0016021 IEA
    membrane GO:0016020 IEA
    plasma membrane GO:0005886 ISO
 Experiment description of studies that identified Lpar6 in exosomes
1
Experiment ID 15
ISEV standards
✔
EM
EV Biophysical techniques
✘ EV Cytosolic markers
✔
CD63
EV Membrane markers
✘ EV Negative markers
✘ EV Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 17486113    
Organism Mus musculus
Homo sapiens
Experiment description Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Authors Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO
Journal name NCB
Publication year 2007
Sample Mast cells
Sample name MC9
Bone marrow-derived mast cells
HMC-1
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.11-1.21 g/mL
Molecules identified in the study Protein
mRNA
miRNA
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
Microarray
miRCURY LNA Array
 Protein-protein interactions for Lpar6
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Lpar6 is involved
PathwayEvidenceSource
G alpha (q) signalling events IEA Reactome
G alpha (q) signalling events IEA Reactome
P2Y receptors IEA Reactome





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