Gene description for Nanp
Gene name N-acetylneuraminic acid phosphatase
Gene symbol Nanp
Other names/aliases 1600031M04Rik
Hdhd4
Species Mus musculus
 Database cross references - Nanp
ExoCarta ExoCarta_67311
Vesiclepedia VP_67311
Entrez Gene 67311
UniProt Q9CPT3  
 Nanp identified in sEVs derived from the following tissue/cell type
Mast cells 17486113    
 Gene ontology annotations for Nanp
Molecular Function
    N-acylneuraminate-9-phosphatase activity GO:0050124 IBA
    N-acylneuraminate-9-phosphatase activity GO:0050124 ISO
    N-acylneuraminate-9-phosphatase activity GO:0050124 ISS
Biological Process
    N-acetylglucosamine biosynthetic process GO:0006045 IEA
    N-acetylneuraminate metabolic process GO:0006054 IMP
    CMP-N-acetylneuraminate biosynthetic process GO:0006055 IEA
    CMP-N-acetylneuraminate biosynthetic process GO:0006055 IMP
    N-acetylneuraminate biosynthetic process GO:0046380 IBA
    N-acetylneuraminate biosynthetic process GO:0046380 ISO
    N-acetylneuraminate biosynthetic process GO:0046380 ISS
    glycosylation GO:0070085 IEA
Subcellular Localization
    cellular_component GO:0005575 ND
    cytosol GO:0005829 ISO
 Experiment description of studies that identified Nanp in sEVs
1
Experiment ID 15
MISEV standards
✔
EM
Biophysical techniques
✔
CD63
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 17486113    
Organism Mus musculus
Homo sapiens
Experiment description Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Authors "Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO"
Journal name NCB
Publication year 2007
Sample Mast cells
Sample name MC9
Bone marrow-derived mast cells
HMC-1
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.11-1.21 g/mL
Molecules identified in the study Protein
mRNA
miRNA
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
Microarray
miRCURY LNA Array
 Protein-protein interactions for Nanp
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.



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