Gene description for Pnpla8
Gene name	patatin-like phospholipase domain containing 8
Gene symbol	Pnpla8
Other names/aliases	1200006O19Rik AI467579 Ipla2(gamma)
Species	Mus musculus
Database cross references - Pnpla8
ExoCarta	ExoCarta_67452
Vesiclepedia	VP_67452
Entrez Gene	67452
UniProt	Q8K1N1
Pnpla8 identified in sEVs derived from the following tissue/cell type
Neural stem cells	25242146

Gene ontology annotations for Pnpla8

Molecular Function     lysophospholipase activity GO:0004622 IEA     phospholipase A1 activity GO:0008970 IEA     calcium-dependent phospholipase A2 activity GO:0047498 IEA     calcium-independent phospholipase A2 activity GO:0047499 IBA     calcium-independent phospholipase A2 activity GO:0047499 IMP     calcium-independent phospholipase A2 activity GO:0047499 ISO     calcium-independent phospholipase A2 activity GO:0047499 ISS Biological Process     prostaglandin biosynthetic process GO:0001516 IEA     prostaglandin biosynthetic process GO:0001516 ISO     fatty acid metabolic process GO:0006631 ISO     fatty acid metabolic process GO:0006631 ISS     arachidonate metabolic process GO:0019369 IBA     arachidonate metabolic process GO:0019369 ISO     arachidonate metabolic process GO:0019369 ISS     cardiolipin metabolic process GO:0032048 IMP     cardiolipin metabolic process GO:0032048 ISO     phosphatidylcholine catabolic process GO:0034638 IEA     phosphatidylcholine catabolic process GO:0034638 ISO     intracellular signal transduction GO:0035556 IEA     intracellular signal transduction GO:0035556 ISO     linoleic acid metabolic process GO:0043651 IEA     linoleic acid metabolic process GO:0043651 ISO     phosphatidylethanolamine catabolic process GO:0046338 IEA     phosphatidylethanolamine catabolic process GO:0046338 ISO     arachidonate secretion GO:0050482 IEA     arachidonate secretion GO:0050482 ISO     lipid homeostasis GO:0055088 IMP     lipid homeostasis GO:0055088 ISO     triglyceride homeostasis GO:0070328 IMP     triglyceride homeostasis GO:0070328 ISO     regulation of cellular response to oxidative stress GO:1900407 IMP Subcellular Localization     mitochondrion GO:0005739 IDA     peroxisome GO:0005777 IDA     peroxisome GO:0005777 ISO     peroxisomal membrane GO:0005778 ISO     peroxisomal membrane GO:0005778 ISS     endoplasmic reticulum membrane GO:0005789 IEA     membrane GO:0016020 IBA     membrane GO:0016020 ISO     membrane GO:0016020 ISS     mitochondrial membrane GO:0031966 IEA