Gene description for Nek10
Gene name NIMA (never in mitosis gene a)- related kinase 10
Gene symbol Nek10
Other names/aliases Gm282
Species Mus musculus
 Database cross references - Nek10
ExoCarta ExoCarta_674895
Entrez Gene 674895
UniProt Q3UGM2  
 Nek10 identified in exosomes derived from the following tissue/cell type
Pancreatic cells 19351151    
 Gene ontology annotations for Nek10
Molecular Function
    transferase activity GO:0016740 IEA
    nucleotide binding GO:0000166 IEA
    protein kinase activity GO:0004672 IEA
    ATP binding GO:0005524 IEA
    protein serine/threonine kinase activity GO:0004674 IBA
    transferase activity, transferring phosphorus-containing groups GO:0016772 IEA
    metal ion binding GO:0046872 IEA
    kinase activity GO:0016301 IEA
Biological Process
    phosphorylation GO:0016310 IEA
    protein phosphorylation GO:0006468 IBA
Subcellular Localization
    cellular_component GO:0005575 ND
 Experiment description of studies that identified Nek10 in exosomes
1
Experiment ID 188
ISEV standards
EM
EV Biophysical techniques
GAPDH|UCHL1|HSP90
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19351151    
Organism Mus musculus
Experiment description Characterization of vesicles secreted from insulinoma NIT-1 cells.
Authors Lee HS, Jeong J, Lee KJ.
Journal name J Proteome Res
Publication year 2009
Sample Pancreatic cells
Sample name Pancreatic beta cell (NIT-1)
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for Nek10
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Nek10 is involved
No pathways found





Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here