Gene description for Nudt7
Gene name nudix (nucleoside diphosphate linked moiety X)-type motif 7
Gene symbol Nudt7
Other names/aliases 1300007B24Rik
2210404C19Rik
Species Mus musculus
 Database cross references - Nudt7
ExoCarta ExoCarta_67528
Vesiclepedia VP_67528
Entrez Gene 67528
UniProt Q99P30  
 Nudt7 identified in sEVs derived from the following tissue/cell type
Mast cells 17486113    
 Gene ontology annotations for Nudt7
Molecular Function
    magnesium ion binding GO:0000287 IDA
    coenzyme A diphosphatase activity GO:0010945 IDA
    coenzyme A diphosphatase activity GO:0010945 TAS
    manganese ion binding GO:0030145 IEA
    snoRNA binding GO:0030515 IDA
    5'-(N(7)-methylguanosine 5'-triphospho)-[mRNA] hydrolase activity GO:0140933 IDA
Biological Process
    nucleoside diphosphate metabolic process GO:0009132 IEA
    coenzyme A catabolic process GO:0015938 IBA
    coenzyme A catabolic process GO:0015938 IDA
    coenzyme A catabolic process GO:0015938 IDA
    medium-chain fatty-acyl-CoA catabolic process GO:0036114 IDA
    butyryl-CoA catabolic process GO:0044580 IDA
    acetyl-CoA catabolic process GO:0046356 IDA
    acetyl-CoA catabolic process GO:0046356 IDA
    brown fat cell differentiation GO:0050873 IDA
    succinyl-CoA catabolic process GO:1901289 IDA
    propionyl-CoA metabolic process GO:1902858 IDA
    propionyl-CoA catabolic process GO:1902859 IDA
    malonyl-CoA catabolic process GO:2001294 IDA
Subcellular Localization
    peroxisome GO:0005777 IDA
    peroxisome GO:0005777 IDA
    peroxisomal matrix GO:0005782 TAS
 Experiment description of studies that identified Nudt7 in sEVs
1
Experiment ID 15
MISEV standards
EM
Biophysical techniques
CD63
Enriched markers
Negative markers
Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 17486113    
Organism Mus musculus
Homo sapiens
Experiment description Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Authors "Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO"
Journal name NCB
Publication year 2007
Sample Mast cells
Sample name MC9
Bone marrow-derived mast cells
HMC-1
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.11-1.21 g/mL
Molecules identified in the study Protein
mRNA
miRNA
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
Microarray
miRCURY LNA Array
 Protein-protein interactions for Nudt7
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 Fitm2  
Negative Genetic Mus musculus
View the network image/svg+xml
 Pathways in which Nudt7 is involved
PathwayEvidenceSource
Peroxisomal protein import IEA Reactome
Protein localization IEA Reactome





Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here