Gene description for Nudt7
Gene name nudix (nucleoside diphosphate linked moiety X)-type motif 7
Gene symbol Nudt7
Other names/aliases 1300007B24Rik
2210404C19Rik
Species Mus musculus
 Database cross references - Nudt7
ExoCarta ExoCarta_67528
Entrez Gene 67528
UniProt Q99P30  
 Nudt7 identified in exosomes derived from the following tissue/cell type
Mast cells 17486113    
 Gene ontology annotations for Nudt7
Molecular Function
    receptor binding GO:0005102 ISO
    hydrolase activity GO:0016787 IEA
    m7G(5')pppN diphosphatase activity GO:0050072 IDA
    dTTP diphosphatase activity GO:0036218 IEA
    manganese ion binding GO:0030145 IEA
    XTP diphosphatase activity GO:0036222 IEA
    UDP-2,3-diacylglucosamine hydrolase activity GO:0008758 IEA
    bis(5'-nucleosyl)-tetraphosphatase activity GO:0008796 IEA
    dihydroneopterin monophosphate phosphatase activity GO:0019176 IEA
    8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity GO:0008413 IEA
    dATP pyrophosphohydrolase activity GO:0008828 IEA
    ATP-dependent 5'-3' DNA helicase activity GO:0043141 IEA
    phosphocholine hydrolase activity GO:0044606 IEA
    acetyl-CoA hydrolase activity GO:0003986 IDA
    magnesium ion binding GO:0000287 IEA
    metal ion binding GO:0046872 IEA
    dITP diphosphatase activity GO:0035870 IEA
    RNA binding GO:0003723 IEA
    pyrophosphatase activity GO:0016462 IEA
    snoRNA binding GO:0030515 IDA
    thiamine-pyrophosphatase activity GO:0004787 IEA
    hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides GO:0016818 IEA
    dihydroneopterin triphosphate pyrophosphohydrolase activity GO:0019177 IEA
Biological Process
    nucleoside diphosphate metabolic process GO:0009132 IEA
    coenzyme A catabolic process GO:0015938 IDA
    brown fat cell differentiation GO:0050873 IDA
    acetyl-CoA catabolic process GO:0046356 IDA
Subcellular Localization
    peroxisome GO:0005777 IDA
 Experiment description of studies that identified Nudt7 in exosomes
1
Experiment ID 15
ISEV standards
✔
EM
EV Biophysical techniques
✘ EV Cytosolic markers
✔
CD63
EV Membrane markers
✘ EV Negative markers
✘ EV Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 17486113    
Organism Mus musculus
Homo sapiens
Experiment description Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Authors Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO
Journal name NCB
Publication year 2007
Sample Mast cells
Sample name MC9
Bone marrow-derived mast cells
HMC-1
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.11-1.21 g/mL
Molecules identified in the study Protein
mRNA
miRNA
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
Microarray
miRCURY LNA Array
 Protein-protein interactions for Nudt7
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Nudt7 is involved
No pathways found





Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here