Gene description for Mfap1a
Gene name microfibrillar-associated protein 1A
Gene symbol Mfap1a
Other names/aliases 4432409M24Rik
Mfap1
Species Mus musculus
 Database cross references - Mfap1a
ExoCarta ExoCarta_67532
Vesiclepedia VP_67532
Entrez Gene 67532
UniProt Q9CQU1  
 Mfap1a identified in sEVs derived from the following tissue/cell type
Mast cells 17486113    
 Gene ontology annotations for Mfap1a
Molecular Function
    extracellular matrix structural constituent GO:0005201 RCA
Biological Process
    mRNA splicing, via spliceosome GO:0000398 IBA
    mRNA splicing, via spliceosome GO:0000398 ISO
    mRNA splicing, via spliceosome GO:0000398 ISS
Subcellular Localization
    microfibril GO:0001527 ISO
    nucleus GO:0005634 ISO
    nucleus GO:0005634 ISS
    nucleoplasm GO:0005654 ISO
    U2-type spliceosomal complex GO:0005684 IBA
    centrosome GO:0005813 ISO
    collagen-containing extracellular matrix GO:0062023 HDA
    U2-type precatalytic spliceosome GO:0071005 ISO
    U2-type precatalytic spliceosome GO:0071005 ISS
 Experiment description of studies that identified Mfap1a in sEVs
1
Experiment ID 15
MISEV standards
EM
Biophysical techniques
CD63
Enriched markers
Negative markers
Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 17486113    
Organism Mus musculus
Homo sapiens
Experiment description Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Authors "Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO"
Journal name NCB
Publication year 2007
Sample Mast cells
Sample name MC9
Bone marrow-derived mast cells
HMC-1
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.11-1.21 g/mL
Molecules identified in the study Protein
mRNA
miRNA
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
Microarray
miRCURY LNA Array
 Protein-protein interactions for Mfap1a
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Mfap1a is involved
No pathways found





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