Gene description for Mfap1a
Gene name microfibrillar-associated protein 1A
Gene symbol Mfap1a
Other names/aliases 4432409M24Rik
Mfap1
Species Mus musculus
 Database cross references - Mfap1a
ExoCarta ExoCarta_67532
Entrez Gene 67532
UniProt Q9CQU1  
 Mfap1a identified in exosomes derived from the following tissue/cell type
Mast cells 17486113    
 Gene ontology annotations for Mfap1a
Molecular Function
    poly(A) RNA binding GO:0044822 ISO
Biological Process
    biological_process GO:0008150 ND
Subcellular Localization
    microfibril GO:0001527 ISO
 Experiment description of studies that identified Mfap1a in exosomes
1
Experiment ID 15
ISEV standards
✔
EM
EV Biophysical techniques
✘ EV Cytosolic markers
✔
CD63
EV Membrane markers
✘ EV Negative markers
✘ EV Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 17486113    
Organism Mus musculus
Homo sapiens
Experiment description Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Authors Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO
Journal name NCB
Publication year 2007
Sample Mast cells
Sample name MC9
Bone marrow-derived mast cells
HMC-1
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.11-1.21 g/mL
Molecules identified in the study Protein
mRNA
miRNA
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
Microarray
miRCURY LNA Array
 Protein-protein interactions for Mfap1a
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Mfap1a is involved
PathwayEvidenceSource
Molecules associated with elastic fibres IEA Reactome





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