Gene description for Prpsap1
Gene name
phosphoribosyl pyrophosphate synthetase-associated protein 1
Gene symbol
Prpsap1
Other names/aliases
5730409F23Rik PAP39
Species
Mus musculus
Database cross references - Prpsap1
ExoCarta
ExoCarta_67763
Vesiclepedia
VP_67763
Entrez Gene
67763
UniProt
Q9D0M1
Prpsap1 identified in sEVs derived from the following tissue/cell type
Melanoma cells
34957415
Melanoma cells
34957415
Gene ontology annotations for Prpsap1
Experiment description of studies that identified Prpsap1 in sEVs
1
Experiment ID
1117
MISEV standards
✘
Biophysical techniques
✔
Cd81|Icam1
Enriched markers
✘
Negative markers
✔
NTA
Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry
PubMed ID
34957415
Organism
Mus musculus
Experiment description
Melanoma-derived small extracellular vesicles induce lymphangiogenesis and metastasis through an NGFR-dependent mechanism
Authors
"GarcÃa-Silva S, Benito-MartÃn A, Nogués L, Hernández-Barranco A, Mazariegos MS, Santos V, Hergueta-Redondo M, Ximénez-Embún P, Kataru RP, Lopez AA, Merino C, Sánchez-Redondo S, Graña-Castro O, Matei I, Nicolás-Avila JÃ, Torres-Ruiz R, RodrÃguez-Perales S, MartÃnez L, Pérez-MartÃnez M, Mata G, Szumera-Ciećkiewicz A, Kalinowska I, Saltari A, MartÃnez-Gómez JM, Hogan SA, Saragovi HU, Ortega S, Garcia-Martin C, Boskovic J, Levesque MP, Rutkowski P, Hidalgo A, Muñoz J, MegÃas D, Mehrara BJ, Lyden D, Peinado H."
Journal name
Nat Cancer
Publication year
2021
Sample
Melanoma cells
Sample name
B16-F1R2
Isolation/purification methods
Differential centrifugation Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Western blotting Mass spectrometry
2
Experiment ID
1118
MISEV standards
✘
Biophysical techniques
✔
Cd81|Icam1
Enriched markers
✘
Negative markers
✔
NTA
Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry
PubMed ID
34957415
Organism
Mus musculus
Experiment description
Melanoma-derived small extracellular vesicles induce lymphangiogenesis and metastasis through an NGFR-dependent mechanism
Authors
"GarcÃa-Silva S, Benito-MartÃn A, Nogués L, Hernández-Barranco A, Mazariegos MS, Santos V, Hergueta-Redondo M, Ximénez-Embún P, Kataru RP, Lopez AA, Merino C, Sánchez-Redondo S, Graña-Castro O, Matei I, Nicolás-Avila JÃ, Torres-Ruiz R, RodrÃguez-Perales S, MartÃnez L, Pérez-MartÃnez M, Mata G, Szumera-Ciećkiewicz A, Kalinowska I, Saltari A, MartÃnez-Gómez JM, Hogan SA, Saragovi HU, Ortega S, Garcia-Martin C, Boskovic J, Levesque MP, Rutkowski P, Hidalgo A, Muñoz J, MegÃas D, Mehrara BJ, Lyden D, Peinado H."
Journal name
Nat Cancer
Publication year
2021
Sample
Melanoma cells
Sample name
B16-F1R2
Isolation/purification methods
Differential centrifugation Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Western blotting Mass spectrometry
Protein-protein interactions for Prpsap1
Protein Interactor
ExoCarta ID
Identification method
PubMed
Species
1
Atxn1
Affinity Capture-MS
Mus musculus
2
Fancd2
Affinity Capture-MS
Mus musculus
View the network
image/svg+xml
Pathways in which Prpsap1 is involved
No pathways found