Gene description for STC1
Gene name stanniocalcin 1
Gene symbol STC1
Other names/aliases STC
Species Homo sapiens
 Database cross references - STC1
ExoCarta ExoCarta_6781
Entrez Gene 6781
HGNC 11373
MIM 601185
UniProt P52823  
 STC1 identified in exosomes derived from the following tissue/cell type
Mesenchymal stem cells Unpublished / Not applicable
 Gene ontology annotations for STC1
Molecular Function
    hormone activity GO:0005179 IEA
Biological Process
    regulation of anion transport GO:0044070 IDA
    cellular response to cAMP GO:0071320 IEA
    bone development GO:0060348 IDA
    negative regulation of renal phosphate excretion GO:1903403 IDA
    regulation of cardiac muscle cell contraction GO:0086004 IDA
    chondrocyte proliferation GO:0035988 IDA
    cellular response to glucocorticoid stimulus GO:0071385 IEA
    cellular response to hypoxia GO:0071456 IEA
    embryo implantation GO:0007566 IEA
    cellular calcium ion homeostasis GO:0006874 IDA
    negative regulation of cell migration GO:0030336 IDA
    negative regulation of calcium ion transport GO:0051926 IDA
    response to vitamin D GO:0033280 IEA
    endothelial cell morphogenesis GO:0001886 IDA
    ossification GO:0001503 IEA
    positive regulation of calcium ion import GO:0090280 IDA
    negative regulation of endothelial cell migration GO:0010596 IDA
    decidualization GO:0046697 IEA
    growth plate cartilage axis specification GO:0003421 IDA
Subcellular Localization
    apical plasma membrane GO:0016324 IEA
    nucleus GO:0005634 IDA
    cytoplasm GO:0005737 IDA
    extracellular space GO:0005615 IEA
 Experiment description of studies that identified STC1 in exosomes
1
Experiment ID 126
ISEV standards
✘ EV Biophysical techniques
✔
GAPDH
EV Cytosolic markers
✘ EV Membrane markers
✘ EV Negative markers
✘ EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry [LTQ-FT Ultra]
PubMed ID Unpublished / Not applicable
Organism Homo sapiens
Experiment description Mesenchymal Stem Cell Exosomes: The Future MSC-based Therapy?
Authors Ruenn Chai Lai, Ronne Wee Yeh Yeo, Soon Sim Tan, Bin Zhang, Yijun Yin, Newman Siu Kwan Sze, Andre Choo, and Sai Kiang Lim
Journal name Mesenchymal Stem Cell Therapy
Publication year 2011
Sample Mesenchymal stem cells
Sample name huES9.E1
Isolation/purification methods HPLC
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Antobody array
Mass spectrometry
 Protein-protein interactions for STC1
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which STC1 is involved
No pathways found





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