Gene description for Mri1
Gene name methylthioribose-1-phosphate isomerase homolog (S. cerevisiae)
Gene symbol Mri1
Other names/aliases 2410018C20Rik
Species Mus musculus
 Database cross references - Mri1
ExoCarta ExoCarta_67873
Vesiclepedia VP_67873
Entrez Gene 67873
UniProt Q9CQT1  
 Mri1 identified in exosomes derived from the following tissue/cell type
Colon cancer cells 37309723    
T-cell lymphoma cells 37309723    
 Gene ontology annotations for Mri1
Molecular Function
    isomerase activity GO:0016853 IEA
    identical protein binding GO:0042802 ISO
    S-methyl-5-thioribose-1-phosphate isomerase activity GO:0046523 IBA
Biological Process
    cellular amino acid biosynthetic process GO:0008652 IEA
    cellular biosynthetic process GO:0044249 IEA
    L-methionine biosynthetic process from methylthioadenosine GO:0019509 IBA
    methionine biosynthetic process GO:0009086 IEA
    cellular metabolic process GO:0044237 IEA
Subcellular Localization
    nucleolus GO:0005730 ISO
    nucleus GO:0005634 IEA
    cytoplasm GO:0005737 ISO
 Experiment description of studies that identified Mri1 in exosomes
1
Experiment ID 907
MISEV standards
✔
EM
EV Biophysical techniques
✔
Tsg101|Sdcbp|Cd151|Gapdh|Lamp2|Cd81|Cd82|Cd9|Cd63|Cd80|Flot2|Tfrc|Rab35|Rab5a
EV Enriched markers
✔
HSPA5
EV Negative markers
✔
NTA
EV Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 37309723    
Organism Mus musculus
Experiment description Proteomic analysis of the small extracellular vesicles and soluble secretory proteins from cachexia inducing and non-inducing cancer cells
Authors Chitti SV, Kang T, Fonseka P, Marzan AL, Stewart S, Shahi S, Bramich K, Ang CS, Pathan M, Gummadi S, Mathivanan S.
Journal name Proteomics
Publication year 2023
Sample Colon cancer cells
Sample name C26
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
2
Experiment ID 908
MISEV standards
✔
EM
EV Biophysical techniques
✔
Tsg101|Sdcbp|Cd151|Gapdh|Lamp2|Cd81|Cd82|Cd9|Cd63|Cd80|Flot2|Tfrc|Rab35|Rab5a
EV Enriched markers
✔
HSPA5
EV Negative markers
✔
NTA
EV Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 37309723    
Organism Mus musculus
Experiment description Proteomic analysis of the small extracellular vesicles and soluble secretory proteins from cachexia inducing and non-inducing cancer cells
Authors Chitti SV, Kang T, Fonseka P, Marzan AL, Stewart S, Shahi S, Bramich K, Ang CS, Pathan M, Gummadi S, Mathivanan S.
Journal name Proteomics
Publication year 2023
Sample T-cell lymphoma cells
Sample name EL4
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
 Protein-protein interactions for Mri1
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Mri1 is involved
PathwayEvidenceSource
Methionine salvage pathway IEA Reactome





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