Gene description for Hist1h1b
Gene name histone cluster 1, H1b
Gene symbol Hist1h1b
Other names/aliases -
Species Rattus norvegicus
 Database cross references - Hist1h1b
ExoCarta ExoCarta_680522
Entrez Gene 680522
UniProt D3ZBN0  
 Hist1h1b identified in exosomes derived from the following tissue/cell type
Reticulocytes 21828046    
Reticulocytes 21828046    
 Gene ontology annotations for Hist1h1b
Molecular Function
    histone deacetylase binding GO:0042826 ISO
    poly(A) RNA binding GO:0044822 ISO
    DNA binding GO:0003677 ISO
    chromatin DNA binding GO:0031490 ISO
Biological Process
    protein stabilization GO:0050821 ISO
    positive regulation of histone H3-K9 methylation GO:0051574 ISO
    nucleosome assembly GO:0006334 IEA
    negative regulation of transcription from RNA polymerase II promoter GO:0000122 ISO
    muscle organ development GO:0007517 ISO
    positive regulation of cell growth GO:0030307 ISO
    chromatin organization GO:0006325 ISO
    establishment of protein localization to chromatin GO:0071169 ISO
Subcellular Localization
    nuclear chromatin GO:0000790 ISO
    nuclear heterochromatin GO:0005720 ISO
    nucleosome GO:0000786 IEA
    extracellular exosome GO:0070062 ISO
 Experiment description of studies that identified Hist1h1b in exosomes
1
Experiment ID 96
ISEV standards
EM
EV Biophysical techniques
TSG101|HSP90|HSC70
EV Cytosolic markers
MHCI
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry [Orbitrap]
PubMed ID 21828046    
Organism Rattus norvegicus
Experiment description The proteo-lipidic composition of exosomes changes during reticulocyte maturation.
Authors Carayon K, Chaoui K, Ronzier E, Lazar I, Bertrand-Michel J, Roques V, Balor S, Terce F, Lopez A, Salome L, Joly E.
Journal name JBC
Publication year 2011
Sample Reticulocytes
Sample name Reticulocytes - D2 Rep 2
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.16-1.21 g/mL
Molecules identified in the study Protein
Lipids
Methods used in the study Mass spectrometry [QSTAR]
Mass spectrometry [Orbitrap]
Western blotting
2
Experiment ID 97
ISEV standards
EM
EV Biophysical techniques
TSG101|HSP90|HSC70
EV Cytosolic markers
MHCI
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry [Orbitrap]
PubMed ID 21828046    
Organism Rattus norvegicus
Experiment description The proteo-lipidic composition of exosomes changes during reticulocyte maturation.
Authors Carayon K, Chaoui K, Ronzier E, Lazar I, Bertrand-Michel J, Roques V, Balor S, Terce F, Lopez A, Salome L, Joly E.
Journal name JBC
Publication year 2011
Sample Reticulocytes
Sample name Reticulocytes - D4 Rep 2
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.16-1.21 g/mL
Molecules identified in the study Protein
Lipids
Methods used in the study Mass spectrometry [QSTAR]
Mass spectrometry [Orbitrap]
Western blotting
 Protein-protein interactions for Hist1h1b
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Hist1h1b is involved
No pathways found





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