Gene description for Fam96a
Gene name family with sequence similarity 96, member A
Gene symbol Fam96a
Other names/aliases 5730536A07Rik
Species Mus musculus
 Database cross references - Fam96a
ExoCarta ExoCarta_68250
Vesiclepedia VP_68250
Entrez Gene 68250
UniProt Q9DCL2  
 Fam96a identified in sEVs derived from the following tissue/cell type
Mast cells 17486113    
 Gene ontology annotations for Fam96a
Molecular Function
    protein binding GO:0005515 IPI
    metal ion binding GO:0046872 IEA
Biological Process
    chromosome segregation GO:0007059 IEA
    iron-sulfur cluster assembly GO:0016226 ISO
    iron-sulfur cluster assembly GO:0016226 ISS
    protein maturation by iron-sulfur cluster transfer GO:0097428 IBA
    protein maturation by iron-sulfur cluster transfer GO:0097428 ISO
    protein maturation by iron-sulfur cluster transfer GO:0097428 ISS
    protein maturation by [4Fe-4S] cluster transfer GO:0106035 IEA
Subcellular Localization
    nucleoplasm GO:0005654 IEA
    nucleoplasm GO:0005654 ISO
    cytosol GO:0005829 ISO
    cytosolic [4Fe-4S] assembly targeting complex GO:0097361 ISO
    cytosolic [4Fe-4S] assembly targeting complex GO:0097361 ISS
 Experiment description of studies that identified Fam96a in sEVs
1
Experiment ID 15
MISEV standards
EM
Biophysical techniques
CD63
Enriched markers
Negative markers
Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 17486113    
Organism Mus musculus
Homo sapiens
Experiment description Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Authors "Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO"
Journal name NCB
Publication year 2007
Sample Mast cells
Sample name MC9
Bone marrow-derived mast cells
HMC-1
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.11-1.21 g/mL
Molecules identified in the study Protein
mRNA
miRNA
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
Microarray
miRCURY LNA Array
 Protein-protein interactions for Fam96a
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Fam96a is involved
No pathways found





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