Gene description for Gstm7
Gene name glutathione S-transferase, mu 7
Gene symbol Gstm7
Other names/aliases 0610005A07Rik
AI894236
Cd203c
Species Mus musculus
 Database cross references - Gstm7
ExoCarta ExoCarta_68312
Vesiclepedia VP_68312
Entrez Gene 68312
UniProt Q80W21  
 Gstm7 identified in exosomes derived from the following tissue/cell type
Mast cells 17486113    
 Gene ontology annotations for Gstm7
Molecular Function
    glutathione transferase activity GO:0004364 IBA
    glutathione transferase activity GO:0004364 IEA
    glutathione transferase activity GO:0004364 ISO
    glutathione peroxidase activity GO:0004602 IEA
    glutathione peroxidase activity GO:0004602 ISO
    signaling receptor binding GO:0005102 IEA
    signaling receptor binding GO:0005102 ISO
    fatty acid binding GO:0005504 IEA
    fatty acid binding GO:0005504 ISO
    enzyme binding GO:0019899 IEA
    enzyme binding GO:0019899 ISO
    protein homodimerization activity GO:0042803 IEA
    protein homodimerization activity GO:0042803 ISO
    glutathione binding GO:0043295 IEA
    glutathione binding GO:0043295 ISO
Biological Process
    glutathione metabolic process GO:0006749 IBA
    glutathione metabolic process GO:0006749 IEA
    glutathione metabolic process GO:0006749 ISO
    regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum GO:0010880 IEA
    regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum GO:0010880 ISO
    nitrobenzene metabolic process GO:0018916 IEA
    nitrobenzene metabolic process GO:0018916 ISO
    xenobiotic catabolic process GO:0042178 IEA
    xenobiotic catabolic process GO:0042178 ISO
    linoleic acid metabolic process GO:0043651 IEA
    linoleic acid metabolic process GO:0043651 ISO
    hepoxilin biosynthetic process GO:0051122 IEA
    hepoxilin biosynthetic process GO:0051122 ISO
    negative regulation of ryanodine-sensitive calcium-release channel activity GO:0060315 ISO
    positive regulation of ryanodine-sensitive calcium-release channel activity GO:0060316 ISO
    cellular detoxification of nitrogen compound GO:0070458 IEA
    cellular detoxification of nitrogen compound GO:0070458 ISO
    cellular response to caffeine GO:0071313 IEA
    cellular response to caffeine GO:0071313 ISO
    cellular oxidant detoxification GO:0098869 IEA
Subcellular Localization
    cytoplasm GO:0005737 ISO
    cytosol GO:0005829 IEA
    cytosol GO:0005829 ISO
    sarcoplasmic reticulum GO:0016529 IEA
    sarcoplasmic reticulum GO:0016529 ISO
    intercellular bridge GO:0045171 IEA
    intercellular bridge GO:0045171 ISO
 Experiment description of studies that identified Gstm7 in exosomes
1
Experiment ID 15
MISEV standards
EM
Biophysical techniques
CD63
Enriched markers
Negative markers
Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 17486113    
Organism Mus musculus
Homo sapiens
Experiment description Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Authors Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO
Journal name NCB
Publication year 2007
Sample Mast cells
Sample name MC9
Bone marrow-derived mast cells
HMC-1
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.11-1.21 g/mL
Molecules identified in the study Protein
mRNA
miRNA
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
Microarray
miRCURY LNA Array
 Protein-protein interactions for Gstm7
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 Lnx1  
Affinity Capture-MS Mus musculus
2 MAPT  
Reconstituted Complex Homo sapiens
View the network image/svg+xml
 Pathways in which Gstm7 is involved
PathwayEvidenceSource
Biological oxidations IEA Reactome
Glutathione conjugation IEA Reactome
Metabolism IEA Reactome
Phase II - Conjugation of compounds IEA Reactome





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