Gene description for LOC683313
Gene name similar to keratin complex 2, basic, gene 6a
Gene symbol LOC683313
Other names/aliases CK-6A
Krt6a
Species Rattus norvegicus
 Database cross references - LOC683313
ExoCarta ExoCarta_683313
Vesiclepedia VP_683313
Entrez Gene 683313
UniProt Q4FZU2  
 LOC683313 identified in sEVs derived from the following tissue/cell type
Adipocytes 25998041    
 Gene ontology annotations for LOC683313
Molecular Function
    structural constituent of skin epidermis GO:0030280 IBA
Biological Process
    morphogenesis of an epithelium GO:0002009 ISS
    keratinization GO:0031424 IBA
    wound healing GO:0042060 ISS
    intermediate filament cytoskeleton organization GO:0045104 ISO
    intermediate filament organization GO:0045109 IBA
Subcellular Localization
    keratin filament GO:0045095 IBA
 Experiment description of studies that identified LOC683313 in sEVs
1
Experiment ID 225
MISEV standards
✔
EM
Biophysical techniques
✔
GAPDH|CD63
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25998041    
Organism Rattus norvegicus
Experiment description Proteomic Analysis of Extracellular Vesicles Released by Adipocytes of Otsuka Long-Evans Tokushima Fatty (OLETF) Rats.
Authors "Lee JE, Moon PG, Lee IK, Baek MC"
Journal name Protein J
Publication year 2015
Sample Adipocytes
Sample name Adipocytes
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
 Protein-protein interactions for LOC683313
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which LOC683313 is involved
PathwayEvidenceSource
Developmental Biology IEA Reactome
Formation of the cornified envelope IEA Reactome
Keratinization IEA Reactome





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