Gene description for Mat2b
Gene name methionine adenosyltransferase II, beta
Gene symbol Mat2b
Other names/aliases -
Species Rattus norvegicus
 Database cross references - Mat2b
ExoCarta ExoCarta_683630
Vesiclepedia VP_683630
Entrez Gene 683630
UniProt Q5U2R0  
 Mat2b identified in sEVs derived from the following tissue/cell type
Pancreatic cancer cells 20124479    
Pancreatic cancer cells 20124479    
 Gene ontology annotations for Mat2b
Molecular Function
    enzyme binding GO:0019899 IEA
    enzyme binding GO:0019899 ISO
    methionine adenosyltransferase regulator activity GO:0048270 IBA
    methionine adenosyltransferase regulator activity GO:0048270 IEA
    methionine adenosyltransferase regulator activity GO:0048270 ISO
    methionine adenosyltransferase regulator activity GO:0048270 ISS
Biological Process
    S-adenosylmethionine biosynthetic process GO:0006556 IBA
    S-adenosylmethionine biosynthetic process GO:0006556 IEA
    S-adenosylmethionine biosynthetic process GO:0006556 ISO
    S-adenosylmethionine biosynthetic process GO:0006556 ISS
    one-carbon metabolic process GO:0006730 IEA
    biological_process GO:0008150 ND
Subcellular Localization
    nucleus GO:0005634 IEA
    nucleus GO:0005634 ISO
    methionine adenosyltransferase complex GO:0048269 IBA
    methionine adenosyltransferase complex GO:0048269 IEA
    methionine adenosyltransferase complex GO:0048269 ISO
    methionine adenosyltransferase complex GO:0048269 ISS
 Experiment description of studies that identified Mat2b in sEVs
1
Experiment ID 92
MISEV standards
✔
EM
Biophysical techniques
✔
HSP70|GAPDH|CD9|CD151
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 20124479    
Organism Rattus norvegicus
Experiment description Cell surface tetraspanin Tspan8 contributes to molecular pathways of exosome-induced endothelial cell activation.
Authors "Nazarenko I, Rana S, Baumann A, McAlear J, Hellwig A, Trendelenburg M, Lochnit G, Preissner KT, Zoller M."
Journal name CR
Publication year 2010
Sample Pancreatic cancer cells
Sample name AS
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density 1.14-1.17 g/mL
Molecules identified in the study Protein
mRNA
Methods used in the study RT-PCR
Western blotting
RatRef-12 Microarray
FACS
Mass spectrometry [MALDI TOF]
2
Experiment ID 93
MISEV standards
✔
EM
Biophysical techniques
✔
HSP70|GAPDH|CD9|CD151
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 20124479    
Organism Rattus norvegicus
Experiment description Cell surface tetraspanin Tspan8 contributes to molecular pathways of exosome-induced endothelial cell activation.
Authors "Nazarenko I, Rana S, Baumann A, McAlear J, Hellwig A, Trendelenburg M, Lochnit G, Preissner KT, Zoller M."
Journal name CR
Publication year 2010
Sample Pancreatic cancer cells
Sample name AS-Tspan8
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density 1.14-1.17 g/mL
Molecules identified in the study Protein
mRNA
Methods used in the study RT-PCR
Western blotting
 Protein-protein interactions for Mat2b
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.



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