Gene description for LOC684819
Gene name similar to H3 histone, family 2 isoform 2
Gene symbol LOC684819
Other names/aliases -
Species Rattus norvegicus
 Database cross references - LOC684819
ExoCarta ExoCarta_684819
Entrez Gene 684819
 LOC684819 identified in exosomes derived from the following tissue/cell type
Adipocytes 25998041    
 Gene ontology annotations for LOC684819
Molecular Function
    DNA binding GO:0003677 IEA
    histone binding GO:0042393 ISO
    protein heterodimerization activity GO:0046982 IEA
Biological Process
    positive regulation of defense response to virus by host GO:0002230 ISO
    protein heterotetramerization GO:0051290 ISO
    regulation of gene silencing GO:0060968 ISO
    nucleosome assembly GO:0006334 ISO
    DNA replication-dependent nucleosome assembly GO:0006335 ISO
Subcellular Localization
    nucleus GO:0005634 ISO
    membrane GO:0016020 ISO
    nucleosome GO:0000786 ISO
    nuclear chromosome GO:0000228 ISO
    nuclear nucleosome GO:0000788 ISO
    chromatin GO:0000785 ISO
    extracellular exosome GO:0070062 ISO
    protein complex GO:0043234 ISO
 Experiment description of studies that identified LOC684819 in exosomes
1
Experiment ID 225
ISEV standards
✔
EM
EV Biophysical techniques
✔
GAPDH
EV Cytosolic markers
✔
CD63
EV Membrane markers
✘ EV Negative markers
✔
NTA
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25998041    
Organism Rattus norvegicus
Experiment description Proteomic Analysis of Extracellular Vesicles Released by Adipocytes of Otsuka Long-Evans Tokushima Fatty (OLETF) Rats.
Authors Lee JE, Moon PG, Lee IK, Baek MC
Journal name Protein J
Publication year 2015
Sample Adipocytes
Sample name Adipocytes
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
 Protein-protein interactions for LOC684819
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which LOC684819 is involved
No pathways found





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