Gene description for Eif4a3
Gene name	eukaryotic translation initiation factor 4A3
Gene symbol	Eif4a3
Other names/aliases	eIF4A-III
Species	Rattus norvegicus
Database cross references - Eif4a3
ExoCarta	ExoCarta_688288
Vesiclepedia	VP_688288
Entrez Gene	688288
UniProt	Q3B8Q2
Eif4a3 identified in sEVs derived from the following tissue/cell type
Reticulocytes	21828046
Reticulocytes	21828046
Reticulocytes	21828046

Gene ontology annotations for Eif4a3

Molecular Function     nucleic acid binding GO:0003676 IEA     DNA clamp loader activity GO:0003689 IEA     RNA helicase activity GO:0003724 IBA     RNA helicase activity GO:0003724 IEA     RNA helicase activity GO:0003724 ISO     mRNA binding GO:0003729 IBA     mRNA binding GO:0003729 ISO     ATP binding GO:0005524 IEA     ATP binding GO:0005524 ISO     poly(A) binding GO:0008143 ISO     hydrolase activity GO:0016787 IEA     ATP hydrolysis activity GO:0016887 IEA     selenocysteine insertion sequence binding GO:0035368 IDA     RNA stem-loop binding GO:0035613 IDA     ribonucleoprotein complex binding GO:0043021 IDA     cohesin loader activity GO:0061775 IEA     chromatin extrusion motor activity GO:0140584 IEA     ATP-dependent H3-H4 histone complex chaperone activity GO:0140665 IEA     ATP-dependent H2AZ histone chaperone activity GO:0140849 IEA Biological Process     nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 IEA     nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 ISO     regulation of alternative mRNA splicing, via spliceosome GO:0000381 ISS     mRNA splicing, via spliceosome GO:0000398 IBA     mRNA splicing, via spliceosome GO:0000398 ISO     mRNA splicing, via spliceosome GO:0000398 ISS     chromatin remodeling GO:0006338 IEA     rRNA processing GO:0006364 IEA     associative learning GO:0008306 IEP     RNA splicing GO:0008380 IEA     negative regulation of gene expression GO:0010629 IMP     response to organic cyclic compound GO:0014070 IEP     negative regulation of translation GO:0017148 ISO     exploration behavior GO:0035640 IEP     positive regulation of translation GO:0045727 ISO     positive regulation of transcription by RNA polymerase II GO:0045944 ISO     positive regulation of mRNA splicing, via spliceosome GO:0048026 ISO     embryonic cranial skeleton morphogenesis GO:0048701 ISO     embryonic cranial skeleton morphogenesis GO:0048701 ISS     mRNA transport GO:0051028 IEA     cellular response to selenite ion GO:0072715 IEP     negative regulation of excitatory postsynaptic potential GO:0090394 IMP     regulation of translation at postsynapse, modulating synaptic transmission GO:0099578 IDA     regulation of translation at postsynapse, modulating synaptic transmission GO:0099578 IMP     chromatin looping GO:0140588 IEA     negative regulation of selenocysteine incorporation GO:1904570 IDA     cellular response to brain-derived neurotrophic factor stimulus GO:1990416 IEP     regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:2000622 ISO Subcellular Localization     nucleus GO:0005634 ISO     nucleoplasm GO:0005654 ISO     spliceosomal complex GO:0005681 IEA     nucleolus GO:0005730 IBA     cytoplasm GO:0005737 ISO     nuclear speck GO:0016607 IEA     dendrite GO:0030425 IDA     exon-exon junction complex GO:0035145 ISO     neuronal cell body GO:0043025 IDA     U2-type catalytic step 1 spliceosome GO:0071006 ISO     U2-type catalytic step 1 spliceosome GO:0071006 ISS     catalytic step 2 spliceosome GO:0071013 IBA     catalytic step 2 spliceosome GO:0071013 ISO     postsynapse GO:0098794 IEA     glutamatergic synapse GO:0098978 IDA     glutamatergic synapse GO:0098978 IMP     ribonucleoprotein complex GO:1990904 IDA