ExoCarta: Gene summary

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Gene description for LOC689899
Gene name	similar to 60S ribosomal protein L23a
Gene symbol	LOC689899
Other names/aliases	-
Species	Rattus norvegicus
Database cross references - LOC689899
ExoCarta	ExoCarta_689899
Entrez Gene	689899
LOC689899 identified in exosomes derived from the following tissue/cell type
Reticulocytes	21828046
Reticulocytes	21828046

Gene ontology annotations for LOC689899

Molecular Function
	nucleotide binding	GO:0000166	IEA
	structural constituent of ribosome	GO:0003735	IEA
	poly(A) RNA binding	GO:0044822	IEA
Biological Process
	translation	GO:0006412	IEA
	cell proliferation	GO:0008283	IEA
Subcellular Localization
	cytosolic large ribosomal subunit	GO:0022625	IEA
	TORC2 complex	GO:0031932	ISO
	extracellular exosome	GO:0070062	IEA
	nucleus	GO:0005634	IEA

Experiment description of studies that identified LOC689899 in exosomes

Experiment ID

ISEV standards
✔ EM	EV Biophysical techniques
✔ TSG101\|HSP90\|HSC70	EV Cytosolic markers
✔ MHCI	EV Membrane markers
✘	EV Negative markers
✘	EV Particle analysis

Identified molecule

protein

Identification method

Mass spectrometry [Orbitrap]

PubMed ID

21828046

Organism

Rattus norvegicus

Experiment description

The proteo-lipidic composition of exosomes changes during reticulocyte maturation.

Authors

Carayon K, Chaoui K, Ronzier E, Lazar I, Bertrand-Michel J, Roques V, Balor S, Terce F, Lopez A, Salome L, Joly E.

Journal name

JBC

Publication year

2011

Sample

Reticulocytes

Sample name

Reticulocytes - D2 Rep 2

Isolation/purification methods

Differential centrifugation
Ultracentrifugation
Sucrose density gradient

Flotation density

1.16-1.21 g/mL

Molecules identified in the study

Protein
Lipids

Methods used in the study

Mass spectrometry [QSTAR]
Mass spectrometry [Orbitrap]
Western blotting