Gene description for Zg16
Gene name zymogen granule protein 16
Gene symbol Zg16
Other names/aliases 1810010M01Rik
AI593689
ZG16p
Species Mus musculus
 Database cross references - Zg16
ExoCarta ExoCarta_69036
Vesiclepedia VP_69036
Entrez Gene 69036
UniProt Q8K0C5  
 Zg16 identified in sEVs derived from the following tissue/cell type
Faeces 33431899    
Faeces 33431899    
 Gene ontology annotations for Zg16
Molecular Function
    carbohydrate binding GO:0030246 IEA
    peptidoglycan binding GO:0042834 IDA
Biological Process
    cytokine production GO:0001816 IMP
    protein transport GO:0015031 IEA
    type II interferon production GO:0032609 IMP
    interleukin-4 production GO:0032633 IMP
    interleukin-6 production GO:0032635 IMP
    tumor necrosis factor production GO:0032640 IMP
    defense response to Gram-positive bacterium GO:0050830 IMP
    suppression of symbiont entry into host GO:0052373 IMP
Subcellular Localization
    extracellular space GO:0005615 IBA
    Golgi lumen GO:0005796 ISO
    Golgi lumen GO:0005796 ISS
    zymogen granule membrane GO:0042589 IEA
    zymogen granule membrane GO:0042589 ISO
    collagen-containing extracellular matrix GO:0062023 ISO
    collagen-containing extracellular matrix GO:0062023 ISS
    mucus layer GO:0070701 IDA
 Experiment description of studies that identified Zg16 in sEVs
1
Experiment ID 303
MISEV standards
EM
Biophysical techniques
Cd63|Cd81|Cd9
Enriched markers
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33431899    
Organism Mus musculus
Experiment description High-fat diet-induced upregulation of exosomal phosphatidylcholine contributes to insulin resistance
Authors "Kumar A, Sundaram K, Mu J, Dryden GW, Sriwastva MK, Lei C, Zhang L, Qiu X, Xu F, Yan J, Zhang X, Park JW, Merchant ML, Bohler HCL, Wang B, Zhang S, Qin C, Xu Z, Han X, McClain CJ, Teng Y, Zhang HG."
Journal name Nat Commun
Publication year 2021
Sample Faeces
Sample name Intestinal epithelial cells - C57BL/6
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Lipid
miRNA
Methods used in the study Western blotting
Mass spectrometry
Immunofluorescence
miRNA array
HPLC
2
Experiment ID 304
MISEV standards
EM
Biophysical techniques
Cd63|Cd81|Cd9
Enriched markers
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33431899    
Organism Mus musculus
Experiment description High-fat diet-induced upregulation of exosomal phosphatidylcholine contributes to insulin resistance
Authors "Kumar A, Sundaram K, Mu J, Dryden GW, Sriwastva MK, Lei C, Zhang L, Qiu X, Xu F, Yan J, Zhang X, Park JW, Merchant ML, Bohler HCL, Wang B, Zhang S, Qin C, Xu Z, Han X, McClain CJ, Teng Y, Zhang HG."
Journal name Nat Commun
Publication year 2021
Sample Faeces
Sample name Intestinal epithelial cells - C57BL/6
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Lipid
miRNA
Methods used in the study Western blotting
Mass spectrometry
Immunofluorescence
miRNA array
HPLC
 Protein-protein interactions for Zg16
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Zg16 is involved
No pathways found





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