Gene description for Gys1
Gene name glycogen synthase 1, muscle
Gene symbol Gys1
Other names/aliases -
Species Rattus norvegicus
 Database cross references - Gys1
ExoCarta ExoCarta_690987
Entrez Gene 690987
UniProt A2RRU1  
 Gys1 identified in exosomes derived from the following tissue/cell type
Reticulocytes 21828046    
 Gene ontology annotations for Gys1
Molecular Function
    glucose binding GO:0005536 IDA
    glycogen (starch) synthase activity GO:0004373 ISO
    glycogen synthase activity, transferring glucose-1-phosphate GO:0061547 ISO
    protein kinase binding GO:0019901 ISO
Biological Process
    glycogen biosynthetic process GO:0005978 ISO
    heart development GO:0007507 ISO
    glycogen metabolic process GO:0005977 IDA
Subcellular Localization
    cytoplasm GO:0005737 ISO
    membrane GO:0016020 ISO
    inclusion body GO:0016234 ISO
 Experiment description of studies that identified Gys1 in exosomes
1
Experiment ID 96
ISEV standards
✔
EM
EV Biophysical techniques
✔
TSG101|HSP90|HSC70
EV Cytosolic markers
✔
MHCI
EV Membrane markers
✘ EV Negative markers
✘ EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry [Orbitrap]
PubMed ID 21828046    
Organism Rattus norvegicus
Experiment description The proteo-lipidic composition of exosomes changes during reticulocyte maturation.
Authors Carayon K, Chaoui K, Ronzier E, Lazar I, Bertrand-Michel J, Roques V, Balor S, Terce F, Lopez A, Salome L, Joly E.
Journal name JBC
Publication year 2011
Sample Reticulocytes
Sample name Reticulocytes - D2 Rep 2
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.16-1.21 g/mL
Molecules identified in the study Protein
Lipids
Methods used in the study Mass spectrometry [QSTAR]
Mass spectrometry [Orbitrap]
Western blotting
 Protein-protein interactions for Gys1
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Gys1 is involved
PathwayEvidenceSource
Glycogen synthesis IEA Reactome





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