Gene description for Kmt2e
Gene name	lysine (K)-specific methyltransferase 2E
Gene symbol	Kmt2e
Other names/aliases	1810033J14Rik 9530077A04Rik D230038D11Rik Mll5 NKp44L
Species	Mus musculus
Database cross references - Kmt2e
ExoCarta	ExoCarta_69188
Entrez Gene	69188
UniProt	Q3UG20
Kmt2e identified in exosomes derived from the following tissue/cell type
Mast cells	17486113

Gene ontology annotations for Kmt2e

Molecular Function     zinc ion binding GO:0008270 IEA     enzyme binding GO:0019899 ISO     histone-lysine N-methyltransferase activity GO:0018024 IEA     transferase activity GO:0016740 IEA     methyltransferase activity GO:0008168 IEA     histone methyltransferase activity (H3-K4 specific) GO:0042800 ISO     metal ion binding GO:0046872 IEA     transcription coactivator activity GO:0003713 ISO Biological Process     positive regulation of granulocyte differentiation GO:0030854 ISO     regulation of transcription, DNA-templated GO:0006355 IEA     histone H3-K4 methylation GO:0051568 ISO     cell cycle arrest GO:0007050 IEA     cellular response to retinoic acid GO:0071300 ISO     methylation GO:0032259 IEA     cell cycle GO:0007049 IEA     DNA methylation GO:0006306 IMP     positive regulation of transcription, DNA-templated GO:0045893 ISO     chromatin modification GO:0016568 IEA     retinoic acid receptor signaling pathway GO:0048384 ISO     transcription, DNA-templated GO:0006351 IEA     erythrocyte differentiation GO:0030218 IMP     neutrophil mediated immunity GO:0002446 IMP     neutrophil activation GO:0042119 IMP Subcellular Localization     intercellular bridge GO:0045171 ISO     intracellular membrane-bounded organelle GO:0043231 ISO     nucleoplasm GO:0005654 ISO     MLL5-L complex GO:0070688 ISO     nucleus GO:0005634 IEA