Gene description for Gp1ba
Gene name glycoprotein Ib (platelet), alpha polypeptide
Gene symbol Gp1ba
Other names/aliases -
Species Rattus norvegicus
 Database cross references - Gp1ba
ExoCarta ExoCarta_691992
Vesiclepedia VP_691992
Entrez Gene 691992
 Gp1ba identified in sEVs derived from the following tissue/cell type
Reticulocytes 21828046    
 Gene ontology annotations for Gp1ba
Biological Process
    cell morphogenesis GO:0000902 ISO
    cell adhesion GO:0007155 ISO
    blood coagulation GO:0007596 ISO
    blood coagulation GO:0007596 ISO
    blood coagulation, intrinsic pathway GO:0007597 ISO
    hemostasis GO:0007599 ISO
    positive regulation of platelet activation GO:0010572 ISO
    megakaryocyte development GO:0035855 ISO
    fibrinolysis GO:0042730 ISO
    release of sequestered calcium ion into cytosol GO:0051209 ISO
    positive regulation of leukocyte tethering or rolling GO:1903238 IMP
Subcellular Localization
    extracellular space GO:0005615 IBA
    plasma membrane GO:0005886 ISO
    external side of plasma membrane GO:0009897 ISO
    cell surface GO:0009986 ISO
    membrane GO:0016020 ISO
    extracellular matrix GO:0031012 IBA
    glycoprotein Ib-IX-V complex GO:1990779 ISO
 Experiment description of studies that identified Gp1ba in sEVs
1
Experiment ID 97
MISEV standards
EM
Biophysical techniques
TSG101|HSP90|HSC70|MHCI
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry [Orbitrap]
PubMed ID 21828046    
Organism Rattus norvegicus
Experiment description The proteo-lipidic composition of exosomes changes during reticulocyte maturation.
Authors "Carayon K, Chaoui K, Ronzier E, Lazar I, Bertrand-Michel J, Roques V, Balor S, Terce F, Lopez A, Salome L, Joly E."
Journal name JBC
Publication year 2011
Sample Reticulocytes
Sample name Reticulocytes - D4 Rep 2
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.16-1.21 g/mL
Molecules identified in the study Protein
Lipids
Methods used in the study Mass spectrometry [QSTAR]
Mass spectrometry [Orbitrap]
Western blotting
 Protein-protein interactions for Gp1ba
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Gp1ba is involved
No pathways found





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