Gene description for Dcps
Gene name decapping enzyme, scavenger
Gene symbol Dcps
Other names/aliases 1700001E16Rik
AA408441
Species Mus musculus
 Database cross references - Dcps
ExoCarta ExoCarta_69305
Entrez Gene 69305
UniProt Q9DAR7  
 Dcps identified in exosomes derived from the following tissue/cell type
Pancreatic cells 19351151    
 Gene ontology annotations for Dcps
Molecular Function
    catalytic activity GO:0003824 IEA
    hydrolase activity GO:0016787 IEA
    RNA 7-methylguanosine cap binding GO:0000340 ISO
    m7G(5')pppN diphosphatase activity GO:0050072 ISO
Biological Process
    RNA splicing GO:0008380 IEA
    negative regulation of programmed cell death GO:0043069 ISO
    mRNA cis splicing, via spliceosome GO:0045292 ISO
    mRNA processing GO:0006397 IEA
    deadenylation-dependent decapping of nuclear-transcribed mRNA GO:0000290 IEA
    cellular response to menadione GO:0036245 ISO
Subcellular Localization
    nucleus GO:0005634 ISO
    mitochondrion GO:0005739 ISO
    cytoplasm GO:0005737 ISO
    nucleoplasm GO:0005654 ISO
 Experiment description of studies that identified Dcps in exosomes
1
Experiment ID 188
ISEV standards
✔
EM
EV Biophysical techniques
✔
GAPDH|UCHL1|HSP90
EV Cytosolic markers
✘ EV Membrane markers
✘ EV Negative markers
✘ EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19351151    
Organism Mus musculus
Experiment description Characterization of vesicles secreted from insulinoma NIT-1 cells.
Authors Lee HS, Jeong J, Lee KJ.
Journal name J Proteome Res
Publication year 2009
Sample Pancreatic cells
Sample name Pancreatic beta cell (NIT-1)
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for Dcps
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Dcps is involved
PathwayEvidenceSource
mRNA decay by 3' to 5' exoribonuclease IEA Reactome





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