Gene description for Dcps
Gene name decapping enzyme, scavenger
Gene symbol Dcps
Other names/aliases 1700001E16Rik
AA408441
Species Mus musculus
 Database cross references - Dcps
ExoCarta ExoCarta_69305
Vesiclepedia VP_69305
Entrez Gene 69305
UniProt Q9DAR7  
 Dcps identified in exosomes derived from the following tissue/cell type
Pancreatic cells 19351151    
 Gene ontology annotations for Dcps
Molecular Function
    RNA 7-methylguanosine cap binding GO:0000340 IBA
    RNA 7-methylguanosine cap binding GO:0000340 ISO
    RNA 7-methylguanosine cap binding GO:0000340 ISS
    identical protein binding GO:0042802 IEA
    identical protein binding GO:0042802 ISO
    5'-(N(7)-methyl 5'-triphosphoguanosine)-[mRNA] diphosphatase activity GO:0140932 ISO
    5'-(N(7)-methyl 5'-triphosphoguanosine)-[mRNA] diphosphatase activity GO:0140932 ISS
Biological Process
    deadenylation-dependent decapping of nuclear-transcribed mRNA GO:0000290 IBA
    deadenylation-dependent decapping of nuclear-transcribed mRNA GO:0000290 IEA
    mRNA cis splicing, via spliceosome GO:0045292 ISO
    mRNA cis splicing, via spliceosome GO:0045292 ISS
    mRNA methylguanosine-cap decapping GO:0110156 ISO
Subcellular Localization
    P-body GO:0000932 IBA
    nucleus GO:0005634 IBA
    nucleus GO:0005634 ISO
    nucleus GO:0005634 ISS
    nucleoplasm GO:0005654 IEA
    nucleoplasm GO:0005654 ISO
    cytoplasm GO:0005737 ISO
    cytoplasm GO:0005737 ISS
    mitochondrion GO:0005739 IEA
    mitochondrion GO:0005739 ISO
    cytosol GO:0005829 IEA
    cytosol GO:0005829 ISO
 Experiment description of studies that identified Dcps in exosomes
1
Experiment ID 188
MISEV standards
EM
Biophysical techniques
GAPDH|UCHL1|HSP90
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19351151    
Organism Mus musculus
Experiment description Characterization of vesicles secreted from insulinoma NIT-1 cells.
Authors Lee HS, Jeong J, Lee KJ.
Journal name J Proteome Res
Publication year 2009
Sample Pancreatic cells
Sample name Pancreatic beta cell (NIT-1)
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for Dcps
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Dcps is involved
PathwayEvidenceSource
Deadenylation-dependent mRNA decay IEA Reactome
Metabolism of RNA IEA Reactome
mRNA decay by 3' to 5' exoribonuclease IEA Reactome





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