Gene description for Dennd6b
Gene name DENN/MADD domain containing 6B
Gene symbol Dennd6b
Other names/aliases 1700027J05Rik
AI414881
Fam116b
Species Mus musculus
 Database cross references - Dennd6b
ExoCarta ExoCarta_69440
Vesiclepedia VP_69440
Entrez Gene 69440
UniProt Q9D9V7  
 Dennd6b identified in sEVs derived from the following tissue/cell type
Mast cells 17486113    
 Gene ontology annotations for Dennd6b
Molecular Function
    guanyl-nucleotide exchange factor activity GO:0005085 ISO
    guanyl-nucleotide exchange factor activity GO:0005085 ISS
Subcellular Localization
    recycling endosome GO:0055037 IBA
    recycling endosome GO:0055037 IEA
 Experiment description of studies that identified Dennd6b in sEVs
1
Experiment ID 15
MISEV standards
✔
EM
Biophysical techniques
✔
CD63
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 17486113    
Organism Mus musculus
Homo sapiens
Experiment description Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Authors "Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO"
Journal name NCB
Publication year 2007
Sample Mast cells
Sample name MC9
Bone marrow-derived mast cells
HMC-1
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.11-1.21 g/mL
Molecules identified in the study Protein
mRNA
miRNA
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
Microarray
miRCURY LNA Array
 Protein-protein interactions for Dennd6b
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.



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