Gene description for Capns2
Gene name calpain, small subunit 2
Gene symbol Capns2
Other names/aliases 2310005G05Rik
30K-2
Species Mus musculus
 Database cross references - Capns2
ExoCarta ExoCarta_69543
Vesiclepedia VP_69543
Entrez Gene 69543
UniProt Q9D7J7  
 Capns2 identified in sEVs derived from the following tissue/cell type
Fibroblasts 23260141    
 Gene ontology annotations for Capns2
Molecular Function
    calcium-dependent cysteine-type endopeptidase activity GO:0004198 IEA
    calcium ion binding GO:0005509 IEA
    protein binding GO:0005515 IPI
Subcellular Localization
    cytoplasm GO:0005737 IEA
    plasma membrane GO:0005886 TAS
    calpain complex GO:0110158 IBA
 Experiment description of studies that identified Capns2 in sEVs
1
Experiment ID 210
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|FLOT1
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23260141    
Organism Mus musculus
Experiment description Exosomes Mediate Stromal Mobilization of Autocrine Wnt-PCP Signaling in Breast Cancer Cell Migration.
Authors "Luga V, Zhang L, Viloria-Petit AM, Ogunjimi AA, Inanlou MR, Chiu E, Buchanan M, Hosein AN, Basik M, Wrana JL."
Journal name Cell
Publication year 2012
Sample Fibroblasts
Sample name Normal-Fibroblasts (L cells)
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for Capns2
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 Fzr1  
Affinity Capture-MS Mus musculus
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