Gene description for Tmem30a
Gene name transmembrane protein 30A
Gene symbol Tmem30a
Other names/aliases 2010200I23Rik
AW540225
Cdc50a
D9Wsu20e
Species Mus musculus
 Database cross references - Tmem30a
ExoCarta ExoCarta_69981
Vesiclepedia VP_69981
Entrez Gene 69981
UniProt Q8VEK0  
 Tmem30a identified in exosomes derived from the following tissue/cell type
Colon cancer cells 37309723    
T-cell lymphoma cells 37309723    
 Gene ontology annotations for Tmem30a
Molecular Function
    protein binding GO:0005515 IPI
Biological Process
    phospholipid translocation GO:0045332 ISO
    phospholipid transport GO:0015914 IEA
    transport GO:0006810 IEA
    drug transmembrane transport GO:0006855 ISO
    positive regulation of protein exit from endoplasmic reticulum GO:0070863 ISO
    protein localization to endosome GO:0036010 ISO
    neuron projection development GO:0031175 ISO
    positive regulation of neuron projection development GO:0010976 IDA
    lipid transport GO:0006869 IEA
Subcellular Localization
    cytoplasmic vesicle GO:0031410 IEA
    Golgi apparatus GO:0005794 IEA
    membrane GO:0016020 ISO
    endoplasmic reticulum GO:0005783 ISO
    plasma membrane GO:0005886 IEA
    integral component of membrane GO:0016021 IEA
 Experiment description of studies that identified Tmem30a in exosomes
1
Experiment ID 907
MISEV standards
EM
EV Biophysical techniques
Tsg101|Sdcbp|Cd151|Gapdh|Lamp2|Cd81|Cd82|Cd9|Cd63|Cd80|Flot2|Tfrc|Rab35|Rab5a
EV Enriched markers
HSPA5
EV Negative markers
NTA
EV Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 37309723    
Organism Mus musculus
Experiment description Proteomic analysis of the small extracellular vesicles and soluble secretory proteins from cachexia inducing and non-inducing cancer cells
Authors Chitti SV, Kang T, Fonseka P, Marzan AL, Stewart S, Shahi S, Bramich K, Ang CS, Pathan M, Gummadi S, Mathivanan S.
Journal name Proteomics
Publication year 2023
Sample Colon cancer cells
Sample name C26
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
2
Experiment ID 908
MISEV standards
EM
EV Biophysical techniques
Tsg101|Sdcbp|Cd151|Gapdh|Lamp2|Cd81|Cd82|Cd9|Cd63|Cd80|Flot2|Tfrc|Rab35|Rab5a
EV Enriched markers
HSPA5
EV Negative markers
NTA
EV Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 37309723    
Organism Mus musculus
Experiment description Proteomic analysis of the small extracellular vesicles and soluble secretory proteins from cachexia inducing and non-inducing cancer cells
Authors Chitti SV, Kang T, Fonseka P, Marzan AL, Stewart S, Shahi S, Bramich K, Ang CS, Pathan M, Gummadi S, Mathivanan S.
Journal name Proteomics
Publication year 2023
Sample T-cell lymphoma cells
Sample name EL4
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
 Protein-protein interactions for Tmem30a
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Tmem30a is involved
No pathways found





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